Chemical constituents of the fermented broth of the ascomycete theissenia cinerea 89091602

Wen Li Liang, Che Jen Hsiao, Yu Ming Ju, Liang Hsin Lee, Zong-Huei Li

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

One new betaenone, theissenoic acid (1), together with three new acetogenins, theissenolactones A-C (2-4, resp.), were isolated from the fermented broth of Theissenia cinerea 89091602 isolated in Taiwan. The structures of 1-4 were elucidated by spectroscopic methods. Biological tests revealed that 3 and 4 exhibited moderate growth-inhibitory activities against A549 lung cancer cell line with GI 50 values of 14.9 and 47.9Î?M, respectively.

Original languageEnglish
Pages (from-to)2285-2290
Number of pages6
JournalChemistry and Biodiversity
Volume8
Issue number12
DOIs
Publication statusPublished - Dec 2011

Fingerprint

Acetogenins
Ascomycota
Taiwan
Lung Neoplasms
Cells
Cell Line
Acids
Growth
2,3,7,7a-tetrahydro-3-hydroxy-7-methyl-2-(prop-1-en-1-yl)-5H-furo(3,4-b)pyran-5-one

ASJC Scopus subject areas

  • Biochemistry
  • Chemistry(all)
  • Bioengineering
  • Molecular Biology
  • Molecular Medicine

Cite this

Chemical constituents of the fermented broth of the ascomycete theissenia cinerea 89091602. / Liang, Wen Li; Hsiao, Che Jen; Ju, Yu Ming; Lee, Liang Hsin; Li, Zong-Huei.

In: Chemistry and Biodiversity, Vol. 8, No. 12, 12.2011, p. 2285-2290.

Research output: Contribution to journalArticle

Liang, Wen Li ; Hsiao, Che Jen ; Ju, Yu Ming ; Lee, Liang Hsin ; Li, Zong-Huei. / Chemical constituents of the fermented broth of the ascomycete theissenia cinerea 89091602. In: Chemistry and Biodiversity. 2011 ; Vol. 8, No. 12. pp. 2285-2290.
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