Chemical constituents of the fermented broth of the ascomycete theissenia cinerea 89091602

Wen Li Liang, Che Jen Hsiao, Yu Ming Ju, Liang Hsin Lee, Zong-Huei Li

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

One new betaenone, theissenoic acid (1), together with three new acetogenins, theissenolactones A-C (2-4, resp.), were isolated from the fermented broth of Theissenia cinerea 89091602 isolated in Taiwan. The structures of 1-4 were elucidated by spectroscopic methods. Biological tests revealed that 3 and 4 exhibited moderate growth-inhibitory activities against A549 lung cancer cell line with GI 50 values of 14.9 and 47.9Î?M, respectively.

Original languageEnglish
Pages (from-to)2285-2290
Number of pages6
JournalChemistry and Biodiversity
Volume8
Issue number12
DOIs
Publication statusPublished - Dec 2011

ASJC Scopus subject areas

  • Biochemistry
  • Chemistry(all)
  • Bioengineering
  • Molecular Biology
  • Molecular Medicine

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