Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina

Yu Ming Ju, Guei Jane Wang, Chun Yao Chen, Ya Jing Tsau, Chang Hung Chou, Zong-Huei Li

Research output: Contribution to journalArticle

Abstract

Lacrymarone (1), a novel diterpenoid, together with seven known compounds 2-8 were isolated from the fermented broth and mycelium of Lacrymaria velutina, an edible fungus collected in Taiwan. The structures of 1-8 were elucidated by analyzing their spectroscopic data. Further biological tests revealed that the co-crystal of 7 and 8 exhibited a moderate inducible nitric oxide synthase (iNOS) inhibitory activity, and with an IC50 value of 59.54 ± 3.74 μM.

Original languageEnglish
Pages (from-to)311-315
Number of pages5
JournalBotanical Studies
Volume51
Issue number3
Publication statusPublished - Jul 2010

Fingerprint

edible fungi
Basidiomycota
diterpenoids
mycelium
inhibitory concentration 50
crystals
Taiwan
testing
inducible nitric oxide synthase

Keywords

  • Basidiomycete
  • Inducible nitric oxide synthase (iNOS)
  • Lacrymaria velutina
  • Lacrymarone

ASJC Scopus subject areas

  • Plant Science

Cite this

Ju, Y. M., Wang, G. J., Chen, C. Y., Tsau, Y. J., Chou, C. H., & Li, Z-H. (2010). Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina. Botanical Studies, 51(3), 311-315.

Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina. / Ju, Yu Ming; Wang, Guei Jane; Chen, Chun Yao; Tsau, Ya Jing; Chou, Chang Hung; Li, Zong-Huei.

In: Botanical Studies, Vol. 51, No. 3, 07.2010, p. 311-315.

Research output: Contribution to journalArticle

Ju, YM, Wang, GJ, Chen, CY, Tsau, YJ, Chou, CH & Li, Z-H 2010, 'Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina', Botanical Studies, vol. 51, no. 3, pp. 311-315.
Ju YM, Wang GJ, Chen CY, Tsau YJ, Chou CH, Li Z-H. Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina. Botanical Studies. 2010 Jul;51(3):311-315.
Ju, Yu Ming ; Wang, Guei Jane ; Chen, Chun Yao ; Tsau, Ya Jing ; Chou, Chang Hung ; Li, Zong-Huei. / Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina. In: Botanical Studies. 2010 ; Vol. 51, No. 3. pp. 311-315.
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