Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina

Yu Ming Ju, Guei Jane Wang, Chun Yao Chen, Ya Jing Tsau, Chang Hung Chou, Zong-Huei Li

Research output: Contribution to journalArticle

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Abstract

Lacrymarone (1), a novel diterpenoid, together with seven known compounds 2-8 were isolated from the fermented broth and mycelium of Lacrymaria velutina, an edible fungus collected in Taiwan. The structures of 1-8 were elucidated by analyzing their spectroscopic data. Further biological tests revealed that the co-crystal of 7 and 8 exhibited a moderate inducible nitric oxide synthase (iNOS) inhibitory activity, and with an IC50 value of 59.54 ± 3.74 μM.

Original languageEnglish
Pages (from-to)311-315
Number of pages5
JournalBotanical Studies
Volume51
Issue number3
Publication statusPublished - Jul 2010

Keywords

  • Basidiomycete
  • Inducible nitric oxide synthase (iNOS)
  • Lacrymaria velutina
  • Lacrymarone

ASJC Scopus subject areas

  • Plant Science

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    Ju, Y. M., Wang, G. J., Chen, C. Y., Tsau, Y. J., Chou, C. H., & Li, Z-H. (2010). Chemical constituents from fermented broth and mycelium of the basidiomycete Lacrymaria velutina. Botanical Studies, 51(3), 311-315.