Characteristics of patients with bleeding peptic ulcer requiring emergency endoscopy and aggressive treatment

C. L. Perng, H. J. Lin, C. J. Chen, F. Y. Lee, S. D. Lee, C. H. Lee

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Objectives: Patients with an ulcer and active bleeding or a nonbleeding, visible vessel are high-risk for further bleeding and should receive aggressive therapy. In this study, we tried to identify clinical parameters that predict these high-risk groups. Methods: Over a 7-month period, 16 clinical parameters were analyzed prospectively in 316 patients with bleeding peptic ulcer. A multivariate analysis was used to find the independent predictors for the high-risk patients. Results: A total of 114 patients (36%) was found to have a spurting hemorrhage (eight patients), oozing hemorrhage (27 patients), or a nonbleeding visible vessel (79 patients). Using an univariate analysis, a statistically significant predictor was the appearance of coffee ground fluid or blood from the nasogastric tube. This predictor also emerged as an independent factor (odds ratio, 0.4333; 95% confidence interval, 0.263-0.714). Conclusions: Patients with bleeding peptic ulcer who have coffee ground fluid or blood from the nasogastric tube should receive an emergency endoscopy and aggressive treatment.

Original languageEnglish
Pages (from-to)1811-1814
Number of pages4
JournalAmerican Journal of Gastroenterology
Volume89
Issue number10
Publication statusPublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Characteristics of patients with bleeding peptic ulcer requiring emergency endoscopy and aggressive treatment'. Together they form a unique fingerprint.

  • Cite this