Characteristics of amebic liver abscess in patients with or without human immunodeficiency virus

Kuan Jung Chen, Chin Hui Yang, Yi Chun Lin, Hsin Yi Liu, Say Tsung Liao, Yuarn Jang Lee

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background and purpose: Amebic liver abscess (ALA) is the most common extra-intestinal amebiasis. This study was performed to review the clinical features of patients with amebic liver abscesses and compare them in Taiwanese patients with or without human immunodeficiency virus (HIV). Methods: The medical charts of 27 inpatients with ALA treated at the Taipei Medical University Hospital, Taipei, Taiwan, were retrospectively analyzed. ALA was defined as positive findings of indirect hemagglutination test (IHA) and imaging study. Patients were divided into 2 groups according to their HIV infection status. Results: The most common clinical symptoms were fever (89.9%) and abdominal pain (81%). The mean white blood cell count in HIV-uninfected patients was significantly higher than in infected patients (17,830 ± 4,722/μL vs 11,549 ± 5,325/μL; p < 0.01). The aspartate aminotransferase levels were significantly lower in HIV-infected patients than in uninfected patients (85.7 ± 59.1 IU/L vs 31.7 ± 21.2 IU/L; p < 0.01). Three HIV-uninfected patients and 10 infected patients had IHA titer >1:1024 (p < 0.05). The duration of hospital stay was longer for HIV-uninfected patients than for infected patients (24.8 ± 14.6 days vs 11.6 ± 5.9 days; p <0.05) Conclusions: HIV-infected patients with ALA had a more insidious onset of illness, significantly lower white cell count and liver enzymes, and shorter duration of hospital stay than uninfected patients. Physicians should be alert to ALA for early diagnosis and treatment.

Original languageEnglish
Pages (from-to)500-504
Number of pages5
JournalJournal of Microbiology, Immunology and Infection
Volume42
Issue number6
Publication statusPublished - Dec 1 2009

Fingerprint

Amoebic Liver Abscess
HIV
Length of Stay
Amoebic Dysentery
Hemagglutination Tests
Virus Diseases
Taiwan
Leukocyte Count
Abdominal Pain
Inpatients
Early Diagnosis
Fever
Cell Count
Physicians

Keywords

  • Amebic
  • Entamoeba histolytica
  • HIV
  • Liver abscess

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Characteristics of amebic liver abscess in patients with or without human immunodeficiency virus. / Chen, Kuan Jung; Yang, Chin Hui; Lin, Yi Chun; Liu, Hsin Yi; Liao, Say Tsung; Lee, Yuarn Jang.

In: Journal of Microbiology, Immunology and Infection, Vol. 42, No. 6, 01.12.2009, p. 500-504.

Research output: Contribution to journalArticle

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