Changes of cerebral blood and tissue oxygenation in temporal lobe epilepsy shown by near infrared spectroscopy

Y. Oana, C. Wang, A. Hoshika, Y. Takei, N. Sakaue, N. Hirabayashi, M. Kaneko

Research output: Contribution to journalArticle

Abstract

Near infrared spectroscopy (NIRS) appears to be a safe, noninvasive technique useful in the EEG laboratory. NIRS has been used for continuous monitoring of changes in blood and tissue oxygenation of the whole brain. We report our observations of changes in local cerebral oxygenation in temporal lobe epilepsy. Eleven patients (four men, seven women; average age 31.9 years) including two patients after surgical treatment were selected by identifing temporal lobe atrophy and lateralizing the epileptic focus, by means of MRI, SPECT and EEG. Using NIRS (Hamamatsu Photonics Co., Hamamatsu, Shizuoka, Japan), changes in cerebral blood and tissue of oxygenated haemoglobin (HbO2) and deoxygenated haemoglobin (HbR) produced by hyperventilation (HV) were measured in both the temporal region with the atrophy and the contralateral temporal region. In both temporal regions, HbO2 values decreased from baseline (at start of HV) after the end of HV, but there was no difference between temporal region with atrophy and contralateral temporal region. However, in nine cases except two cases after surgical treatment, there was difference between them when HV ended. HbR values changed from baseline, but there was no difference between temporal region and contralateral region. Because of results, it is suggested that NIRS may be useful for one of supplementary diagnosis of temporal lobe epilepsy, but it is necessary to investigate further.

Original languageEnglish
Pages (from-to)109-116
Number of pages8
JournalJournal of the Japan Epilepsy Society
Volume16
Issue number2
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Near-Infrared Spectroscopy
Temporal Lobe Epilepsy
Temporal Lobe
Hyperventilation
Atrophy
Electroencephalography
Hemoglobins
Optics and Photonics
Single-Photon Emission-Computed Tomography
Japan
Brain
Therapeutics

Keywords

  • Changes in cerebral oxygenation
  • Epileptogenic focus
  • MRI
  • Near infrared spectroscopy
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Oana, Y., Wang, C., Hoshika, A., Takei, Y., Sakaue, N., Hirabayashi, N., & Kaneko, M. (1998). Changes of cerebral blood and tissue oxygenation in temporal lobe epilepsy shown by near infrared spectroscopy. Journal of the Japan Epilepsy Society, 16(2), 109-116.

Changes of cerebral blood and tissue oxygenation in temporal lobe epilepsy shown by near infrared spectroscopy. / Oana, Y.; Wang, C.; Hoshika, A.; Takei, Y.; Sakaue, N.; Hirabayashi, N.; Kaneko, M.

In: Journal of the Japan Epilepsy Society, Vol. 16, No. 2, 1998, p. 109-116.

Research output: Contribution to journalArticle

Oana, Y, Wang, C, Hoshika, A, Takei, Y, Sakaue, N, Hirabayashi, N & Kaneko, M 1998, 'Changes of cerebral blood and tissue oxygenation in temporal lobe epilepsy shown by near infrared spectroscopy', Journal of the Japan Epilepsy Society, vol. 16, no. 2, pp. 109-116.
Oana, Y. ; Wang, C. ; Hoshika, A. ; Takei, Y. ; Sakaue, N. ; Hirabayashi, N. ; Kaneko, M. / Changes of cerebral blood and tissue oxygenation in temporal lobe epilepsy shown by near infrared spectroscopy. In: Journal of the Japan Epilepsy Society. 1998 ; Vol. 16, No. 2. pp. 109-116.
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