Changes in activation of the auditory cortex following long-term amplification: An fMRI study

Juen Haur Hwang, Chang Wei Wu, Jyh Horng Chen, Tien Chen Liu

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Conclusion. Speech-elicited activation decreased after monaural amplification bilaterally during unaided or aided ear stimulation, but tended to recover later at the contralateral hemisphere during aided ear stimulation. Objectives. The purpose of this study was to investigate the changes in the activation pattern of auditory cortex following long-term monoaural amplification. Patients and methods. Serial functional magnetic resonance images were obtained while speech sounds were presented to the aided (right) and unaided (left) ears of eight hearing-impaired subjects before, 3 months, and 9 months after beginning the use of a single hearing aid. The results were analyzed by group analysis. Results. Before hearing aid fitting, we found that activation patterns of the auditory cortex were somewhat segmented in the left hemisphere, regardless of whether the speech sounds were delivered to right or left ear. Cross projection was lost in response to right ear stimulation. After hearing aid fitting, on the unaided side stimulation, the activation tended to decrease progressively on both sides 3 months and 9 months after beginning monoaural amplification. On the aided side stimulation, activation also decreased 3 months after amplification bilaterally, but tended to recover at the contralateral hemisphere after 9 months of amplification. Cross projection was restored in response to right ear stimulation.

Original languageEnglish
Pages (from-to)1275-1280
Number of pages6
JournalActa Oto-Laryngologica
Volume126
Issue number12
DOIs
Publication statusPublished - Dec 1 2006
Externally publishedYes

Fingerprint

Auditory Cortex
Ear
Magnetic Resonance Imaging
Hearing Aids
Phonetics
Hearing
Magnetic Resonance Spectroscopy

Keywords

  • Amplification
  • fMRI
  • Hearing-aid
  • Human
  • Plasticity

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Changes in activation of the auditory cortex following long-term amplification : An fMRI study. / Hwang, Juen Haur; Wu, Chang Wei; Chen, Jyh Horng; Liu, Tien Chen.

In: Acta Oto-Laryngologica, Vol. 126, No. 12, 01.12.2006, p. 1275-1280.

Research output: Contribution to journalArticle

Hwang, Juen Haur ; Wu, Chang Wei ; Chen, Jyh Horng ; Liu, Tien Chen. / Changes in activation of the auditory cortex following long-term amplification : An fMRI study. In: Acta Oto-Laryngologica. 2006 ; Vol. 126, No. 12. pp. 1275-1280.
@article{3a7bf23259fd4b5298e08b5e3b26e92c,
title = "Changes in activation of the auditory cortex following long-term amplification: An fMRI study",
abstract = "Conclusion. Speech-elicited activation decreased after monaural amplification bilaterally during unaided or aided ear stimulation, but tended to recover later at the contralateral hemisphere during aided ear stimulation. Objectives. The purpose of this study was to investigate the changes in the activation pattern of auditory cortex following long-term monoaural amplification. Patients and methods. Serial functional magnetic resonance images were obtained while speech sounds were presented to the aided (right) and unaided (left) ears of eight hearing-impaired subjects before, 3 months, and 9 months after beginning the use of a single hearing aid. The results were analyzed by group analysis. Results. Before hearing aid fitting, we found that activation patterns of the auditory cortex were somewhat segmented in the left hemisphere, regardless of whether the speech sounds were delivered to right or left ear. Cross projection was lost in response to right ear stimulation. After hearing aid fitting, on the unaided side stimulation, the activation tended to decrease progressively on both sides 3 months and 9 months after beginning monoaural amplification. On the aided side stimulation, activation also decreased 3 months after amplification bilaterally, but tended to recover at the contralateral hemisphere after 9 months of amplification. Cross projection was restored in response to right ear stimulation.",
keywords = "Amplification, fMRI, Hearing-aid, Human, Plasticity",
author = "Hwang, {Juen Haur} and Wu, {Chang Wei} and Chen, {Jyh Horng} and Liu, {Tien Chen}",
year = "2006",
month = "12",
day = "1",
doi = "10.1080/00016480600794503",
language = "English",
volume = "126",
pages = "1275--1280",
journal = "Acta Oto-Laryngologica",
issn = "0001-6489",
publisher = "Informa Healthcare",
number = "12",

}

TY - JOUR

T1 - Changes in activation of the auditory cortex following long-term amplification

T2 - An fMRI study

AU - Hwang, Juen Haur

AU - Wu, Chang Wei

AU - Chen, Jyh Horng

AU - Liu, Tien Chen

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Conclusion. Speech-elicited activation decreased after monaural amplification bilaterally during unaided or aided ear stimulation, but tended to recover later at the contralateral hemisphere during aided ear stimulation. Objectives. The purpose of this study was to investigate the changes in the activation pattern of auditory cortex following long-term monoaural amplification. Patients and methods. Serial functional magnetic resonance images were obtained while speech sounds were presented to the aided (right) and unaided (left) ears of eight hearing-impaired subjects before, 3 months, and 9 months after beginning the use of a single hearing aid. The results were analyzed by group analysis. Results. Before hearing aid fitting, we found that activation patterns of the auditory cortex were somewhat segmented in the left hemisphere, regardless of whether the speech sounds were delivered to right or left ear. Cross projection was lost in response to right ear stimulation. After hearing aid fitting, on the unaided side stimulation, the activation tended to decrease progressively on both sides 3 months and 9 months after beginning monoaural amplification. On the aided side stimulation, activation also decreased 3 months after amplification bilaterally, but tended to recover at the contralateral hemisphere after 9 months of amplification. Cross projection was restored in response to right ear stimulation.

AB - Conclusion. Speech-elicited activation decreased after monaural amplification bilaterally during unaided or aided ear stimulation, but tended to recover later at the contralateral hemisphere during aided ear stimulation. Objectives. The purpose of this study was to investigate the changes in the activation pattern of auditory cortex following long-term monoaural amplification. Patients and methods. Serial functional magnetic resonance images were obtained while speech sounds were presented to the aided (right) and unaided (left) ears of eight hearing-impaired subjects before, 3 months, and 9 months after beginning the use of a single hearing aid. The results were analyzed by group analysis. Results. Before hearing aid fitting, we found that activation patterns of the auditory cortex were somewhat segmented in the left hemisphere, regardless of whether the speech sounds were delivered to right or left ear. Cross projection was lost in response to right ear stimulation. After hearing aid fitting, on the unaided side stimulation, the activation tended to decrease progressively on both sides 3 months and 9 months after beginning monoaural amplification. On the aided side stimulation, activation also decreased 3 months after amplification bilaterally, but tended to recover at the contralateral hemisphere after 9 months of amplification. Cross projection was restored in response to right ear stimulation.

KW - Amplification

KW - fMRI

KW - Hearing-aid

KW - Human

KW - Plasticity

UR - http://www.scopus.com/inward/record.url?scp=33751098258&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33751098258&partnerID=8YFLogxK

U2 - 10.1080/00016480600794503

DO - 10.1080/00016480600794503

M3 - Article

C2 - 17101588

AN - SCOPUS:33751098258

VL - 126

SP - 1275

EP - 1280

JO - Acta Oto-Laryngologica

JF - Acta Oto-Laryngologica

SN - 0001-6489

IS - 12

ER -