Central Corneal Thickness of Normal-Tension Glaucoma and Non-Glaucoma Populations in Ethnic Chinese

Hung Chiao Chen, Jau Der Ho, Shirley Hseuh Li Chang, Yi Hsin Sidney Chen, Shiu Chen Wu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: The variations in central corneal thickness can influence intraocular pressure measurement. The aim of our study was to determine whether there is a difference in the central corneal thickness between normal-tension glaucoma (NTG) and non-glaucoma populations. Methods: This prospective study included 33 consecutive patients with NTG and 33 age- and gender-matched healthy subjects as control subjects. The NTG patients were grouped according to the refractive error into group 1 (spherical equivalent +2.5 D ∼ -6.0 D) and group 2 (spherical equivalent more than -6.0 D). Central corneal thickness was measured using a ultrasonic pachymeter. The mean central corneal thickness of the NTG and healthy subjects were compared using the student t-test and Nilcoxon Rank Sum test. Results: The mean (±SD) central corneal thickness in the healthy subjects and NTG patients was 554.1 (±36.3) and 547.2 (±31.4) microns, respectively. There were no statistical significant differences between these two groups (p=0.411). The median central corneal thickness in the NTG group 1 and group 2 eyes was 545, and 547.5 microns, respectively. The difference was not statistically significant, either (p=0.799). Ten patients (30%) of NTG had high myopia (group 2), and their median age was 38.5 years old, which was significantly younger than that of the group 1 patients (50 years old, p=0.0003). Conclusion: This study indicated that there were no significant differences of central corneal thickness between NTG patients and healthy subjects in our clinic.

Original languageEnglish
Pages (from-to)50-55
Number of pages6
JournalChang Gung Medical Journal
Volume27
Issue number1
Publication statusPublished - Jan 2004

Fingerprint

Low Tension Glaucoma
Population
Healthy Volunteers
Refractive Errors
Nonparametric Statistics
Intraocular Pressure
Ultrasonics
Prospective Studies
Students

Keywords

  • Central corneal thickness
  • Intraocular pressure
  • Myopia
  • Normal-tension glaucoma

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Central Corneal Thickness of Normal-Tension Glaucoma and Non-Glaucoma Populations in Ethnic Chinese. / Chen, Hung Chiao; Ho, Jau Der; Chang, Shirley Hseuh Li; Chen, Yi Hsin Sidney; Wu, Shiu Chen.

In: Chang Gung Medical Journal, Vol. 27, No. 1, 01.2004, p. 50-55.

Research output: Contribution to journalArticle

Chen, Hung Chiao ; Ho, Jau Der ; Chang, Shirley Hseuh Li ; Chen, Yi Hsin Sidney ; Wu, Shiu Chen. / Central Corneal Thickness of Normal-Tension Glaucoma and Non-Glaucoma Populations in Ethnic Chinese. In: Chang Gung Medical Journal. 2004 ; Vol. 27, No. 1. pp. 50-55.
@article{13e09da621b24e909a87263ab96d2dce,
title = "Central Corneal Thickness of Normal-Tension Glaucoma and Non-Glaucoma Populations in Ethnic Chinese",
abstract = "Background: The variations in central corneal thickness can influence intraocular pressure measurement. The aim of our study was to determine whether there is a difference in the central corneal thickness between normal-tension glaucoma (NTG) and non-glaucoma populations. Methods: This prospective study included 33 consecutive patients with NTG and 33 age- and gender-matched healthy subjects as control subjects. The NTG patients were grouped according to the refractive error into group 1 (spherical equivalent +2.5 D ∼ -6.0 D) and group 2 (spherical equivalent more than -6.0 D). Central corneal thickness was measured using a ultrasonic pachymeter. The mean central corneal thickness of the NTG and healthy subjects were compared using the student t-test and Nilcoxon Rank Sum test. Results: The mean (±SD) central corneal thickness in the healthy subjects and NTG patients was 554.1 (±36.3) and 547.2 (±31.4) microns, respectively. There were no statistical significant differences between these two groups (p=0.411). The median central corneal thickness in the NTG group 1 and group 2 eyes was 545, and 547.5 microns, respectively. The difference was not statistically significant, either (p=0.799). Ten patients (30{\%}) of NTG had high myopia (group 2), and their median age was 38.5 years old, which was significantly younger than that of the group 1 patients (50 years old, p=0.0003). Conclusion: This study indicated that there were no significant differences of central corneal thickness between NTG patients and healthy subjects in our clinic.",
keywords = "Central corneal thickness, Intraocular pressure, Myopia, Normal-tension glaucoma",
author = "Chen, {Hung Chiao} and Ho, {Jau Der} and Chang, {Shirley Hseuh Li} and Chen, {Yi Hsin Sidney} and Wu, {Shiu Chen}",
year = "2004",
month = "1",
language = "English",
volume = "27",
pages = "50--55",
journal = "Chang Gung Medical Journal",
issn = "0255-8270",
publisher = "Chang Gung Medical Journal",
number = "1",

}

TY - JOUR

T1 - Central Corneal Thickness of Normal-Tension Glaucoma and Non-Glaucoma Populations in Ethnic Chinese

AU - Chen, Hung Chiao

AU - Ho, Jau Der

AU - Chang, Shirley Hseuh Li

AU - Chen, Yi Hsin Sidney

AU - Wu, Shiu Chen

PY - 2004/1

Y1 - 2004/1

N2 - Background: The variations in central corneal thickness can influence intraocular pressure measurement. The aim of our study was to determine whether there is a difference in the central corneal thickness between normal-tension glaucoma (NTG) and non-glaucoma populations. Methods: This prospective study included 33 consecutive patients with NTG and 33 age- and gender-matched healthy subjects as control subjects. The NTG patients were grouped according to the refractive error into group 1 (spherical equivalent +2.5 D ∼ -6.0 D) and group 2 (spherical equivalent more than -6.0 D). Central corneal thickness was measured using a ultrasonic pachymeter. The mean central corneal thickness of the NTG and healthy subjects were compared using the student t-test and Nilcoxon Rank Sum test. Results: The mean (±SD) central corneal thickness in the healthy subjects and NTG patients was 554.1 (±36.3) and 547.2 (±31.4) microns, respectively. There were no statistical significant differences between these two groups (p=0.411). The median central corneal thickness in the NTG group 1 and group 2 eyes was 545, and 547.5 microns, respectively. The difference was not statistically significant, either (p=0.799). Ten patients (30%) of NTG had high myopia (group 2), and their median age was 38.5 years old, which was significantly younger than that of the group 1 patients (50 years old, p=0.0003). Conclusion: This study indicated that there were no significant differences of central corneal thickness between NTG patients and healthy subjects in our clinic.

AB - Background: The variations in central corneal thickness can influence intraocular pressure measurement. The aim of our study was to determine whether there is a difference in the central corneal thickness between normal-tension glaucoma (NTG) and non-glaucoma populations. Methods: This prospective study included 33 consecutive patients with NTG and 33 age- and gender-matched healthy subjects as control subjects. The NTG patients were grouped according to the refractive error into group 1 (spherical equivalent +2.5 D ∼ -6.0 D) and group 2 (spherical equivalent more than -6.0 D). Central corneal thickness was measured using a ultrasonic pachymeter. The mean central corneal thickness of the NTG and healthy subjects were compared using the student t-test and Nilcoxon Rank Sum test. Results: The mean (±SD) central corneal thickness in the healthy subjects and NTG patients was 554.1 (±36.3) and 547.2 (±31.4) microns, respectively. There were no statistical significant differences between these two groups (p=0.411). The median central corneal thickness in the NTG group 1 and group 2 eyes was 545, and 547.5 microns, respectively. The difference was not statistically significant, either (p=0.799). Ten patients (30%) of NTG had high myopia (group 2), and their median age was 38.5 years old, which was significantly younger than that of the group 1 patients (50 years old, p=0.0003). Conclusion: This study indicated that there were no significant differences of central corneal thickness between NTG patients and healthy subjects in our clinic.

KW - Central corneal thickness

KW - Intraocular pressure

KW - Myopia

KW - Normal-tension glaucoma

UR - http://www.scopus.com/inward/record.url?scp=1642343643&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1642343643&partnerID=8YFLogxK

M3 - Article

C2 - 15074890

AN - SCOPUS:1642343643

VL - 27

SP - 50

EP - 55

JO - Chang Gung Medical Journal

JF - Chang Gung Medical Journal

SN - 0255-8270

IS - 1

ER -