CD8+CD122+ T cell homeostasis is controlled by different levels of IL-15 trans-presentation

Gilbert Aaron Lee, Nan Shih Liao

Research output: Contribution to journalArticlepeer-review

Abstract

The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells require different levels of IL-15 trans-presentation to support their homeostasis.

Original languageEnglish
Pages (from-to)514-517
Number of pages4
JournalJournal of Microbiology, Immunology and Infection
Volume54
Issue number3
DOIs
Publication statusAccepted/In press - 2020

Keywords

  • CD8CD122 T cell homeostasis
  • IL-15

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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