Abstract
The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells require different levels of IL-15 trans-presentation to support their homeostasis.
Original language | English |
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Journal | Journal of Microbiology, Immunology and Infection |
DOIs | |
Publication status | Accepted/In press - 2020 |
Keywords
- CD8CD122 T cell homeostasis
- IL-15
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology and Microbiology(all)
- Microbiology (medical)
- Infectious Diseases