Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy

Wei Shiang Lin, Ching Tai Tai, Ming Hsiung Hsieh, Chin Feng Tsai, Yung Kuo Lin, Hsuan Ming Tsao, Jin Long Huang, Wen Chung Yu, Shih Ping Yang, Yu An Ding, Mau Song Chang, Shih Ann Chen

Research output: Contribution to journalArticle

482 Citations (Scopus)

Abstract

Background - Most of the ectopic beats initiating paroxysmal atrial fibrillation (PAF) originate from the pulmonary vein (PV). However, only limited data are available on PAF originating from the non-PV areas. Methods and Results - Two hundred forty patients with a total of 358 ectopic foci initiating PAF were included. Sixty-eight (28%) patients had AF initiated by ectopic beats (73 foci, 20%) from the non-PV areas, including the left atrial posterior free wall (28, 38.3%), superior vena cava (27, 37.0%), crista terminalis (10, 3,7%), ligament of Marshall (6, 8.2%), coronary sinus ostium (1, 1.4%), and interatrial septum (1, 1.4%). Catheter ablation eliminated AF with acute success rates of 63%, 96%, 100%, 50%, 100%, and 0% in left atrial posterior free wall, superior vena cava, crista terminalis, ligament of Marshall, coronary sinus ostium, and interatrial septum, respectively. During a follow-up period of 22 ± 11 months, 43 patients (63.2%) were free of antiarrhythmic drugs without AF recurrence. Conclusions - Ectopic beats initiating PAF can originate from the non-PV areas, and catheter ablation of the non-PV ectopy has a moderate efficacy in treatment of PAF.

Original languageEnglish
Pages (from-to)3176-3183
Number of pages8
JournalCirculation
Volume107
Issue number25
DOIs
Publication statusPublished - Jul 1 2003
Externally publishedYes

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Catheter Ablation
Atrial Fibrillation
Veins
Superior Vena Cava
Coronary Sinus
Ligaments
Pulmonary Veins
Anti-Arrhythmia Agents
Recurrence

Keywords

  • Ablation
  • Atrial fibrillation
  • Pulmonary vein

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy. / Lin, Wei Shiang; Tai, Ching Tai; Hsieh, Ming Hsiung; Tsai, Chin Feng; Lin, Yung Kuo; Tsao, Hsuan Ming; Huang, Jin Long; Yu, Wen Chung; Yang, Shih Ping; Ding, Yu An; Chang, Mau Song; Chen, Shih Ann.

In: Circulation, Vol. 107, No. 25, 01.07.2003, p. 3176-3183.

Research output: Contribution to journalArticle

Lin, WS, Tai, CT, Hsieh, MH, Tsai, CF, Lin, YK, Tsao, HM, Huang, JL, Yu, WC, Yang, SP, Ding, YA, Chang, MS & Chen, SA 2003, 'Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy', Circulation, vol. 107, no. 25, pp. 3176-3183. https://doi.org/10.1161/01.CIR.0000074206.52056.2D
Lin, Wei Shiang ; Tai, Ching Tai ; Hsieh, Ming Hsiung ; Tsai, Chin Feng ; Lin, Yung Kuo ; Tsao, Hsuan Ming ; Huang, Jin Long ; Yu, Wen Chung ; Yang, Shih Ping ; Ding, Yu An ; Chang, Mau Song ; Chen, Shih Ann. / Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy. In: Circulation. 2003 ; Vol. 107, No. 25. pp. 3176-3183.
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abstract = "Background - Most of the ectopic beats initiating paroxysmal atrial fibrillation (PAF) originate from the pulmonary vein (PV). However, only limited data are available on PAF originating from the non-PV areas. Methods and Results - Two hundred forty patients with a total of 358 ectopic foci initiating PAF were included. Sixty-eight (28{\%}) patients had AF initiated by ectopic beats (73 foci, 20{\%}) from the non-PV areas, including the left atrial posterior free wall (28, 38.3{\%}), superior vena cava (27, 37.0{\%}), crista terminalis (10, 3,7{\%}), ligament of Marshall (6, 8.2{\%}), coronary sinus ostium (1, 1.4{\%}), and interatrial septum (1, 1.4{\%}). Catheter ablation eliminated AF with acute success rates of 63{\%}, 96{\%}, 100{\%}, 50{\%}, 100{\%}, and 0{\%} in left atrial posterior free wall, superior vena cava, crista terminalis, ligament of Marshall, coronary sinus ostium, and interatrial septum, respectively. During a follow-up period of 22 ± 11 months, 43 patients (63.2{\%}) were free of antiarrhythmic drugs without AF recurrence. Conclusions - Ectopic beats initiating PAF can originate from the non-PV areas, and catheter ablation of the non-PV ectopy has a moderate efficacy in treatment of PAF.",
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T1 - Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy

AU - Lin, Wei Shiang

AU - Tai, Ching Tai

AU - Hsieh, Ming Hsiung

AU - Tsai, Chin Feng

AU - Lin, Yung Kuo

AU - Tsao, Hsuan Ming

AU - Huang, Jin Long

AU - Yu, Wen Chung

AU - Yang, Shih Ping

AU - Ding, Yu An

AU - Chang, Mau Song

AU - Chen, Shih Ann

PY - 2003/7/1

Y1 - 2003/7/1

N2 - Background - Most of the ectopic beats initiating paroxysmal atrial fibrillation (PAF) originate from the pulmonary vein (PV). However, only limited data are available on PAF originating from the non-PV areas. Methods and Results - Two hundred forty patients with a total of 358 ectopic foci initiating PAF were included. Sixty-eight (28%) patients had AF initiated by ectopic beats (73 foci, 20%) from the non-PV areas, including the left atrial posterior free wall (28, 38.3%), superior vena cava (27, 37.0%), crista terminalis (10, 3,7%), ligament of Marshall (6, 8.2%), coronary sinus ostium (1, 1.4%), and interatrial septum (1, 1.4%). Catheter ablation eliminated AF with acute success rates of 63%, 96%, 100%, 50%, 100%, and 0% in left atrial posterior free wall, superior vena cava, crista terminalis, ligament of Marshall, coronary sinus ostium, and interatrial septum, respectively. During a follow-up period of 22 ± 11 months, 43 patients (63.2%) were free of antiarrhythmic drugs without AF recurrence. Conclusions - Ectopic beats initiating PAF can originate from the non-PV areas, and catheter ablation of the non-PV ectopy has a moderate efficacy in treatment of PAF.

AB - Background - Most of the ectopic beats initiating paroxysmal atrial fibrillation (PAF) originate from the pulmonary vein (PV). However, only limited data are available on PAF originating from the non-PV areas. Methods and Results - Two hundred forty patients with a total of 358 ectopic foci initiating PAF were included. Sixty-eight (28%) patients had AF initiated by ectopic beats (73 foci, 20%) from the non-PV areas, including the left atrial posterior free wall (28, 38.3%), superior vena cava (27, 37.0%), crista terminalis (10, 3,7%), ligament of Marshall (6, 8.2%), coronary sinus ostium (1, 1.4%), and interatrial septum (1, 1.4%). Catheter ablation eliminated AF with acute success rates of 63%, 96%, 100%, 50%, 100%, and 0% in left atrial posterior free wall, superior vena cava, crista terminalis, ligament of Marshall, coronary sinus ostium, and interatrial septum, respectively. During a follow-up period of 22 ± 11 months, 43 patients (63.2%) were free of antiarrhythmic drugs without AF recurrence. Conclusions - Ectopic beats initiating PAF can originate from the non-PV areas, and catheter ablation of the non-PV ectopy has a moderate efficacy in treatment of PAF.

KW - Ablation

KW - Atrial fibrillation

KW - Pulmonary vein

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