Catastrophic heparin-induced thrombocytopenia/thrombosis syndrome related to the use of a Port-A-Cath in a breast cancer patient receiving chemotherapy

Ming Shen Dai, An Tie Hsieh, Tsu Yi Chao

Research output: Contribution to journalArticle

4 Citations (Scopus)


Heparin-induced thrombocytopenia and thrombosis (HIT/T) syndrome is usually triggered by an immune response after repeated administration of heparin. The syndrome is strongly associated with limb deep vein thrombosis and is potentially life-threatening if unrecognized. We describe the case of a patient with compartment syndrome of the left forearm complicated by HIT/T that developed after Port-A-Cath implantation through the left subclavian vein. Prompt recognition of HIT/T, immediate withdrawal of heparin, and timely institution of thrombolytic therapy successfully prevented limb loss.

Original languageEnglish
Pages (from-to)537-539
Number of pages3
JournalSupportive Care in Cancer
Issue number7
Publication statusPublished - Jul 2004
Externally publishedYes



  • Heparin
  • Heparin-induced thrombocytopenia (HIT)
  • Port-A-Cath
  • Thrombolytic therapy
  • Thrombosis

ASJC Scopus subject areas

  • Oncology
  • Nursing(all)

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