Case report of false-negative diffusion- Weighted image of brain maggnetic resonance imaging (MRI) in acute ischemic stroke

Wei Lun Chang, Ji Ching Lai, Rong Fu Chen, Han Hwa Hu, Chau Shiung Pan

Research output: Contribution to journalArticle


Objective: Challenging differential diagnosis Background: Acute ischemic stroke is a major cause of mortality and morbidity in Taiwan. Diffusion-weighted image (DWI) is a sensitive and common strategy used for imaging acute ischemic stroke. Case report: We present a case of a negative DWI MRI for detecting acute ischemic stroke in a clinical setting. A 75-yearold male had a DWI performed after onset of symptoms suggesting acute ischemic stroke. The initial DWI result was negative at 72 hours of presentation. The neurological symptoms of the patient persisted and DWI was repeated. After 14 days, the DWI data confirmed and demonstrated an acute ischemic stroke. The delay in DWI confirmation, from symptom onset until DWI diagnosis, was 336 hours. Conclusions: DWI may not have 100% sensitivity and accuracy in early stages of acute ischemic stroke. The time course to the development of abnormalities detected by DWI may be longer than anticipated.

Original languageEnglish
Pages (from-to)76-79
Number of pages4
JournalAmerican Journal of Case Reports
Publication statusPublished - Jan 23 2017



  • Diffusion magnetic resonance imaging
  • Neurologic examination
  • Stroke

ASJC Scopus subject areas

  • Medicine(all)

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