Case of pulmonary cryptococcosis mimicking hematogeneous metastases in an immuocompetent patient: Value of absent 18F-fluorodeoxylucose uptake on positron emission tomography/CT scan

Chiao Hua Lee; Ching Tzao; Tsun Hou Chang; Wei Chou Chang; Guo Shu Huang; Chih Kung Lin; Hsin Chung Lin; Hsian He Hsu

doi:10.3348/kjr.2013.14.3.540

Case of pulmonary cryptococcosis mimicking hematogeneous metastases in an immuocompetent patient: Value of absent 18F-fluorodeoxylucose uptake on positron emission tomography/CT scan

Chiao Hua Lee, Ching Tzao, Tsun Hou Chang, Wei Chou Chang, Guo Shu Huang, Chih Kung Lin, Hsin Chung Lin, Hsian He Hsu

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

The radiologic appearance of multiple discrete pulmonary nodules in immunocompetent patients, with cryptococcal infection, has been rarely described. We describe a case of pulmonary cryptococcosis, presenting with bilaterally and randomly distributed nodules on a computed tomography, mimicking hematogeneous metastases. Positron emission tomography does not demonstrate 18F-fluorodeoxyglucose (FDG) uptake, suggesting a low probability for malignancy, which is a crucial piece of information for clinicians when making a management decision. We find the absence of FDG uptake correlates with the pathologic finding of an infectious nodule, composed of fibrosis and necrosis.

Original language	English
Pages (from-to)	540-543
Number of pages	4
Journal	Korean Journal of Radiology
Volume	14
Issue number	3
DOIs	https://doi.org/10.3348/kjr.2013.14.3.540
Publication status	Published - May 2013
Externally published	Yes

Keywords

Cryptococcosis
Multiple pulmonary nodules
Neoplasm metastasis
Positron emission tomography

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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Lee, C. H., Tzao, C., Chang, T. H., Chang, W. C., Huang, G. S., Lin, C. K., Lin, H. C., & Hsu, H. H. (2013). Case of pulmonary cryptococcosis mimicking hematogeneous metastases in an immuocompetent patient: Value of absent 18F-fluorodeoxylucose uptake on positron emission tomography/CT scan. Korean Journal of Radiology, 14(3), 540-543. https://doi.org/10.3348/kjr.2013.14.3.540

Case of pulmonary cryptococcosis mimicking hematogeneous metastases in an immuocompetent patient : Value of absent 18F-fluorodeoxylucose uptake on positron emission tomography/CT scan. / Lee, Chiao Hua; Tzao, Ching; Chang, Tsun Hou; Chang, Wei Chou; Huang, Guo Shu; Lin, Chih Kung; Lin, Hsin Chung; Hsu, Hsian He.

In: Korean Journal of Radiology, Vol. 14, No. 3, 05.2013, p. 540-543.

Research output: Contribution to journal › Article

Lee, Chiao Hua ; Tzao, Ching ; Chang, Tsun Hou ; Chang, Wei Chou ; Huang, Guo Shu ; Lin, Chih Kung ; Lin, Hsin Chung ; Hsu, Hsian He. / Case of pulmonary cryptococcosis mimicking hematogeneous metastases in an immuocompetent patient : Value of absent 18F-fluorodeoxylucose uptake on positron emission tomography/CT scan. In: Korean Journal of Radiology. 2013 ; Vol. 14, No. 3. pp. 540-543.

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abstract = "The radiologic appearance of multiple discrete pulmonary nodules in immunocompetent patients, with cryptococcal infection, has been rarely described. We describe a case of pulmonary cryptococcosis, presenting with bilaterally and randomly distributed nodules on a computed tomography, mimicking hematogeneous metastases. Positron emission tomography does not demonstrate 18F-fluorodeoxyglucose (FDG) uptake, suggesting a low probability for malignancy, which is a crucial piece of information for clinicians when making a management decision. We find the absence of FDG uptake correlates with the pathologic finding of an infectious nodule, composed of fibrosis and necrosis.",

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