Case of pulmonary cryptococcosis mimicking hematogeneous metastases in an immuocompetent patient: Value of absent 18F-fluorodeoxylucose uptake on positron emission tomography/CT scan

Chiao Hua Lee, Ching Tzao, Tsun Hou Chang, Wei Chou Chang, Guo Shu Huang, Chih Kung Lin, Hsin Chung Lin, Hsian He Hsu

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4 Citations (Scopus)


The radiologic appearance of multiple discrete pulmonary nodules in immunocompetent patients, with cryptococcal infection, has been rarely described. We describe a case of pulmonary cryptococcosis, presenting with bilaterally and randomly distributed nodules on a computed tomography, mimicking hematogeneous metastases. Positron emission tomography does not demonstrate 18F-fluorodeoxyglucose (FDG) uptake, suggesting a low probability for malignancy, which is a crucial piece of information for clinicians when making a management decision. We find the absence of FDG uptake correlates with the pathologic finding of an infectious nodule, composed of fibrosis and necrosis.

Original languageEnglish
Pages (from-to)540-543
Number of pages4
JournalKorean Journal of Radiology
Issue number3
Publication statusPublished - May 2013
Externally publishedYes



  • Cryptococcosis
  • Multiple pulmonary nodules
  • Neoplasm metastasis
  • Positron emission tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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