Carriage of antibiotic-resistant pneumococci among Asian children

A multinational surveillance by the Asian Network for Surveillance of Resistant Pathogens (ANSORP)

Yong Lee Nam Yong Lee, J. H. Song, S. Kim, Ran Peck Kyong Ran Peck, K. M. Ahn, S. I. Lee, Y. Yang, J. Li, A. Chongthaleong, S. Tiengrim, N. Aswapokee, T. Y. Lin, J. L. Wu, C. H. Chiu, M. K. Lalitha, K. Thomas, T. Cherian, J. Perera, Teow Yee Ti Teow Yee, F. Jamal & 6 others U. C. Warsa, Hung Van Pham Hung Van, C. C. Carlos, A. M. Shibl, M. R. Jacobs, P. C. Appelbaum

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

To investigate the nasal carriage of antibiotic-resistant pneumococci by children, anterior nasal swabs were done for 4963 children <5 years old in 11 countries in Asia and the Middle East. In total, 1105 pneumococci isolates (carriage rate, 22.3%) were collected, 35.8% of which were found to be nonsusceptible to penicillin. Prevalence of penicillin nonsusceptibility was highest in Taiwan (91.3%), followed by Korea (85.8%), Sri Lanka (76.5%), and Vietnam (70.4%). Penicillin resistance was related to residence in urban areas, enrollment in day care, and a history of otitis media. The most common serogroups were 6 (21.5%), 23 (16.5%), and 19 (15.7%). The most common clone, as assessed by pulsed-field gel electrophoresis, was identical to the Spanish 23F clone and to strains of invasive isolates from adult patients. Data in this study documented the high rate of penicillin or multidrug resistance among isolates of pneumococci carried nasally in children in Asia and the Middle East and showed that this is due to the spread of a few predominant clones in the region.

Original languageEnglish
Pages (from-to)1463-1469
Number of pages7
JournalClinical Infectious Diseases
Volume32
Issue number10
DOIs
Publication statusPublished - May 15 2001
Externally publishedYes

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Streptococcus pneumoniae
Penicillin Resistance
Middle East
Clone Cells
Anti-Bacterial Agents
Nose
Penicillins
Sri Lanka
Vietnam
Pulsed Field Gel Electrophoresis
Otitis Media
Multiple Drug Resistance
Korea
Taiwan

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Carriage of antibiotic-resistant pneumococci among Asian children : A multinational surveillance by the Asian Network for Surveillance of Resistant Pathogens (ANSORP). / Nam Yong Lee, Yong Lee; Song, J. H.; Kim, S.; Kyong Ran Peck, Ran Peck; Ahn, K. M.; Lee, S. I.; Yang, Y.; Li, J.; Chongthaleong, A.; Tiengrim, S.; Aswapokee, N.; Lin, T. Y.; Wu, J. L.; Chiu, C. H.; Lalitha, M. K.; Thomas, K.; Cherian, T.; Perera, J.; Ti Teow Yee, Teow Yee; Jamal, F.; Warsa, U. C.; Pham Hung Van, Hung Van; Carlos, C. C.; Shibl, A. M.; Jacobs, M. R.; Appelbaum, P. C.

In: Clinical Infectious Diseases, Vol. 32, No. 10, 15.05.2001, p. 1463-1469.

Research output: Contribution to journalArticle

Nam Yong Lee, YL, Song, JH, Kim, S, Kyong Ran Peck, RP, Ahn, KM, Lee, SI, Yang, Y, Li, J, Chongthaleong, A, Tiengrim, S, Aswapokee, N, Lin, TY, Wu, JL, Chiu, CH, Lalitha, MK, Thomas, K, Cherian, T, Perera, J, Ti Teow Yee, TY, Jamal, F, Warsa, UC, Pham Hung Van, HV, Carlos, CC, Shibl, AM, Jacobs, MR & Appelbaum, PC 2001, 'Carriage of antibiotic-resistant pneumococci among Asian children: A multinational surveillance by the Asian Network for Surveillance of Resistant Pathogens (ANSORP)', Clinical Infectious Diseases, vol. 32, no. 10, pp. 1463-1469. https://doi.org/10.1086/320165
Nam Yong Lee, Yong Lee ; Song, J. H. ; Kim, S. ; Kyong Ran Peck, Ran Peck ; Ahn, K. M. ; Lee, S. I. ; Yang, Y. ; Li, J. ; Chongthaleong, A. ; Tiengrim, S. ; Aswapokee, N. ; Lin, T. Y. ; Wu, J. L. ; Chiu, C. H. ; Lalitha, M. K. ; Thomas, K. ; Cherian, T. ; Perera, J. ; Ti Teow Yee, Teow Yee ; Jamal, F. ; Warsa, U. C. ; Pham Hung Van, Hung Van ; Carlos, C. C. ; Shibl, A. M. ; Jacobs, M. R. ; Appelbaum, P. C. / Carriage of antibiotic-resistant pneumococci among Asian children : A multinational surveillance by the Asian Network for Surveillance of Resistant Pathogens (ANSORP). In: Clinical Infectious Diseases. 2001 ; Vol. 32, No. 10. pp. 1463-1469.
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AU - Nam Yong Lee, Yong Lee

AU - Song, J. H.

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AU - Kyong Ran Peck, Ran Peck

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AU - Lee, S. I.

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AU - Tiengrim, S.

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AU - Warsa, U. C.

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AU - Carlos, C. C.

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AU - Jacobs, M. R.

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