Calcium bioavailability of calcium carbonate and calcium lactate supplements

Ming Jer Shieh, Fang Hsuean Liao, Shyh Hsiang Lin, Chin Fa Chen, Chung Huei Hsu, Mei Yuh Chung, Yi Wen Chien

Research output: Contribution to journalArticle

Abstract

Calcium intake for the primary prevention of osteoporosis has received much attention. According to the Nutrition and Health Survey in Taiwan, teenage and adult women consume considerably less than the current Recommended Daily Nutrient Allowance (RDNA) of calcium. The purpose of this study was to investigate the calcium bioavailability of calcium carbonate and calcium lactate, two common forms of calcium supplementation. Thirty-eight healthy adults randomly received 900 mg of one of two calcium supplements. Subjects fasted for more than 12 h before taking the calcium supplements. Blood and urine were collected for analysis of serum calcium, serum parathyroid hormone (PTH) at 0, 1, 2, 4, and 5 h, urine calcium at 0, 2, 4, and 5 h, and 24-h urine for creatinine. Results showed that both calcium supplements could increase serum calcium and the urine Ca/creatinine ratio and decrease serum PTH. However, calcium lactate had a faster absorption rate in increasing serum calcium. We concluded that 900-mg calcium supplementation with calcium lactate had higher calcium bioavailabilty compared with calcium carbonate and may produce a greater benefit for the prevention of osteoporosis.

Original languageEnglish
Pages (from-to)34-40
Number of pages7
JournalNutritional Sciences Journal
Volume28
Issue number1
Publication statusPublished - Mar 2003

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Calcium Carbonate
calcium carbonate
Biological Availability
lactates
bioavailability
Calcium
calcium
blood serum
Urine
urine
Serum
Parathyroid Hormone
parathyroid hormone
calcium lactate
Osteoporosis
osteoporosis
Creatinine
creatinine
Recommended Dietary Allowances
Nutrition Surveys

Keywords

  • Calcium bioavailability
  • Calcium carbonate
  • Osteoporosis
  • Parathyroid hormone
  • Serum calcium

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Calcium bioavailability of calcium carbonate and calcium lactate supplements. / Shieh, Ming Jer; Liao, Fang Hsuean; Lin, Shyh Hsiang; Chen, Chin Fa; Hsu, Chung Huei; Chung, Mei Yuh; Chien, Yi Wen.

In: Nutritional Sciences Journal, Vol. 28, No. 1, 03.2003, p. 34-40.

Research output: Contribution to journalArticle

Shieh, Ming Jer ; Liao, Fang Hsuean ; Lin, Shyh Hsiang ; Chen, Chin Fa ; Hsu, Chung Huei ; Chung, Mei Yuh ; Chien, Yi Wen. / Calcium bioavailability of calcium carbonate and calcium lactate supplements. In: Nutritional Sciences Journal. 2003 ; Vol. 28, No. 1. pp. 34-40.
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