Calcinosis cutis complicated by compartment syndrome following extravasation of calcium gluconate in a neonate: A case report

Tuo Kang Chen, Chueh Yuan Yang, Shu Jen Chen

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)

Abstract

Hypocalcemia most frequently occurs in premature neonates. It is usually treated by intravenous (iv) calcium supplementation. However, complications caused by extravasation of iv calcium gluconate include localized soft tissue calcification, necrosis, cellulitis, osteomyelitis, and even compartment syndrome. We present a rare case of iatrogenic calcinosis cutis complicated by compartment syndrome secondary to extravasation of iv calcium gluconate in a neonate. Emergent fasciotomy was performed twice for decompression of compartment syndrome. Histologic findings revealed necrosis and calcification. Appropriate antibiotics were administered to control secondary infection. To the best of our knowledge, there were no previous case reports of calcinosis cutis with compartment syndrome in infants. Although iatrogenic calcinosis cutis is generally a benign entity, the early recognition of the presentation of extravasation of calcium gluconate is important to avoid severe complications and possible medical malpractice disputes. This report aims to raise doctors' awareness of the presentation, course, and management of this relatively rare iatrogenic complication.

Original languageEnglish
Pages (from-to)238-241
Number of pages4
JournalPediatrics and Neonatology
Volume51
Issue number4
DOIs
Publication statusPublished - Jan 1 2010
Externally publishedYes

Keywords

  • Calcinosis cutis
  • Calcium gluconate
  • Compartment syndrome
  • Extravasation
  • Fasciotomy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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