Burkitt's lymphoma in AIDS

Cytogenetic study

J. Whang-Peng, E. C. Lee, H. Sieverts, I. T. Magrath

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Cytogenetic studies were done in two cases of Burkitt's lymphoma in homosexual individuals with possible acquired immune deficiency syndrome (AIDS). The chromosomal abnormalities found are consistent with those previously described in the nonendemic form of Burkitt's lymphoma, with one of the two patients having the variant translocation, t(8;22). The production of the kappa light chain immunoglobulin by the tumor cells from the patient having t(8;22) and the occurrence of the different sites of translocation of the duplication of 1q in the second patient are unusual findings. Whether there is an increase in the incidence of the variant translocation t(8;22) is yet to be determined.

Original languageEnglish
Pages (from-to)818-822
Number of pages5
JournalBlood
Volume63
Issue number4
Publication statusPublished - Jan 1 1984
Externally publishedYes

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Immunoglobulin kappa-Chains
Burkitt Lymphoma
Cytogenetics
Tumors
Acquired Immunodeficiency Syndrome
Cells
Chromosome Aberrations
Incidence
Neoplasms

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

Cite this

Whang-Peng, J., Lee, E. C., Sieverts, H., & Magrath, I. T. (1984). Burkitt's lymphoma in AIDS: Cytogenetic study. Blood, 63(4), 818-822.

Burkitt's lymphoma in AIDS : Cytogenetic study. / Whang-Peng, J.; Lee, E. C.; Sieverts, H.; Magrath, I. T.

In: Blood, Vol. 63, No. 4, 01.01.1984, p. 818-822.

Research output: Contribution to journalArticle

Whang-Peng, J, Lee, EC, Sieverts, H & Magrath, IT 1984, 'Burkitt's lymphoma in AIDS: Cytogenetic study', Blood, vol. 63, no. 4, pp. 818-822.
Whang-Peng J, Lee EC, Sieverts H, Magrath IT. Burkitt's lymphoma in AIDS: Cytogenetic study. Blood. 1984 Jan 1;63(4):818-822.
Whang-Peng, J. ; Lee, E. C. ; Sieverts, H. ; Magrath, I. T. / Burkitt's lymphoma in AIDS : Cytogenetic study. In: Blood. 1984 ; Vol. 63, No. 4. pp. 818-822.
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