Burkitt's lymphoma in AIDS: Cytogenetic study

J. Whang-Peng, E. C. Lee, H. Sieverts, I. T. Magrath

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)

Abstract

Cytogenetic studies were done in two cases of Burkitt's lymphoma in homosexual individuals with possible acquired immune deficiency syndrome (AIDS). The chromosomal abnormalities found are consistent with those previously described in the nonendemic form of Burkitt's lymphoma, with one of the two patients having the variant translocation, t(8;22). The production of the kappa light chain immunoglobulin by the tumor cells from the patient having t(8;22) and the occurrence of the different sites of translocation of the duplication of 1q in the second patient are unusual findings. Whether there is an increase in the incidence of the variant translocation t(8;22) is yet to be determined.

Original languageEnglish
Pages (from-to)818-822
Number of pages5
JournalBlood
Volume63
Issue number4
Publication statusPublished - Jan 1 1984
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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