Burkitt tumor: Tissue culture, cytogenetic and virus studies

Sarah E. Stewart, Elizabeth Lovelace, Jacqueline J. Whang, V. Anomah Ngu

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Tumor cells that retained their original histology were grown from a biopsy taken from a 7-year-ofd male with a Burkitt tumor. The cells grew in suspension, usually in clumps varying from a few to hundreds of cells in a free-floating mass. This cell line was designated SL1. A herpes-like virus, which caused some cell degeneration of the tumor cells in culture, was observed by electron microscopy. Supernatant fluids from the SL1 cultures failed to produce a cytopathogenic effect in inoculated cell lines. A specific chromosome alteration was observed in the cells from the original tumor and in the cultured tumor cells.

Original languageEnglish
Pages (from-to)319-327
Number of pages9
JournalJournal of the National Cancer Institute
Volume34
Issue number2
DOIs
Publication statusPublished - Jan 1 1965
Externally publishedYes

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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