Bupropion improved apathy in behavioral variant frontotemporal dementia: a case report

Chia Pei Lin, Chih Pang Chu, Hsing Cheng Liu

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Apathy is a common neurobehavioral sign in cases of behavioral variant frontotemporal dementia. However, there is still no established sustained effective treatment. We present the case of a 65-year-old man with behavioral variant frontotemporal dementia who suffered from severe apathy, but his apathy improved after a 10-month period of bupropion treatment. His single photon emission computed tomography report also showed slight improvement. To the best of our knowledge, such a case with imaging evidence has never been reported. Further studies to correlate the effects of bupropion on apathy in behavioral variant frontotemporal dementia patients are clearly needed.

Original languageEnglish
Pages (from-to)466-468
Number of pages3
JournalNeurocase
Volume22
Issue number5
DOIs
Publication statusPublished - Sep 2 2016

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Keywords

  • Apathy
  • bupropion
  • dopamine
  • motivation
  • single photon emission computed tomography

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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