Breast cancer multifocality, disease extent, and survival

Tibor Tot, Mária Gere, Gyula Pekár, Miklós Tarján, Syster Hofmeyer, Dan Hellberg, David Lindquist, Tony Hsiu His Chen, Amy Ming Fang Yen, Sherry Yueh Hsia Chiu, László Tabár

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59 Citations (Scopus)

Abstract

The prognostic information implied in subgross morphologic parameters such as lesion distribution (unifocal, multifocal, or diffuse) and disease extent in breast cancer has remained largely unexplored in the literature. We aimed to test whether these parameters influence survival in breast carcinoma. The parameters were assessed in a series of 574 cases, all documented in large-format histology sections. We used Cox proportional hazards regression accompanied by Kaplan-Meyer survival curves, with P

Original languageEnglish
Pages (from-to)1761-1769
Number of pages9
JournalHuman Pathology
Volume42
Issue number11
DOIs
Publication statusPublished - Nov 2011

Keywords

  • Breast cancer
  • Disease extent
  • Large-section histopathology
  • Multifocality
  • Subgross distribution
  • Survival

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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  • Cite this

    Tot, T., Gere, M., Pekár, G., Tarján, M., Hofmeyer, S., Hellberg, D., Lindquist, D., Chen, T. H. H., Yen, A. M. F., Chiu, S. Y. H., & Tabár, L. (2011). Breast cancer multifocality, disease extent, and survival. Human Pathology, 42(11), 1761-1769. https://doi.org/10.1016/j.humpath.2011.02.002