Brain metastases from epithelial ovarian carcinoma: Evaluation of prognosis and managements - A Taiwanese Gynecologic Oncology Group (TGOG) Study

Ying Cheng Chiang, Jian Tai Qiu, Chih Long Chang, Peng Hui Wang, Chih Ming Ho, Wu Chou Lin, Yu Fang Huang, Hao Lin, Chien Hsing Lu, Cheng Yang Chou

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objective: To evaluate the characteristics and outcome of patients with brain metastases from epithelial ovarian carcinoma. Methods: The clinical and pathologic characteristics, treatment and outcome of patients with brain metastases from epithelial ovarian carcinoma were analyzed from eight medical centers in Taiwan under the TGOG (Taiwanese Gynecologic Oncology Group). Results: A total of 64 patients were recruited in this study. The incidence of brain metastases from epithelial ovarian carcinoma seemed to be increasing in recent years. The median survival from the diagnosis of brain metastases was 8 months (range: 0-72). Prior cancer relapse before the diagnosis of brain metastases, number of brain metastases and multimodal treatment were related to the duration of survival. Conclusions: The prognosis for patients with brain metastases from epithelial ovarian carcinoma is generally poor. However, clinicians should keep alert to the neurological complaints of ovarian cancer patients and the patients might benefit from aggressive multimodal treatments.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalGynecologic Oncology
Volume125
Issue number1
DOIs
Publication statusPublished - Apr 2012
Externally publishedYes

Keywords

  • Brain metastases
  • Multimodal treatment
  • Ovarian cancer

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynaecology

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