Abstract

Bone biomarkers included formation, resorption and regulator are released during the bone remodeling processes. These bone biomarkers have attracted much attention in the clinical assessment of osteoporosis treatment in the past decade. Combination with the measurement of bone mineral density, the clinical applications of bone biomarkers have provided comprehensive information for diagnosis of osteoporosis. However, the analytical approaches of the bone biomarkers are still the challenge for further clinical trials. In this mini-review, we have introduced the functions of bone biomarkers and then recently developed techniques for bone biomarker measurements have been systematically integrated to discuss the possibility for osteoporosis assessment in the early stage.

Original languageEnglish
Pages (from-to)18
JournalBiomarker Research
Volume5
DOIs
Publication statusPublished - 2017

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Biomarkers
Osteoporosis
Bone
Bone and Bones
Bone Remodeling
Bone Density
Clinical Trials
Minerals

Cite this

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title = "Bone biomarker for the clinical assessment of osteoporosis: recent developments and future perspectives",
abstract = "Bone biomarkers included formation, resorption and regulator are released during the bone remodeling processes. These bone biomarkers have attracted much attention in the clinical assessment of osteoporosis treatment in the past decade. Combination with the measurement of bone mineral density, the clinical applications of bone biomarkers have provided comprehensive information for diagnosis of osteoporosis. However, the analytical approaches of the bone biomarkers are still the challenge for further clinical trials. In this mini-review, we have introduced the functions of bone biomarkers and then recently developed techniques for bone biomarker measurements have been systematically integrated to discuss the possibility for osteoporosis assessment in the early stage.",
author = "Tsung-Rong Kuo and Chih-Hwa Chen",
year = "2017",
doi = "10.1186/s40364-017-0097-4",
language = "English",
volume = "5",
pages = "18",
journal = "Biomarker Research",
issn = "2050-7771",
publisher = "BioMed Central Ltd.",

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T2 - recent developments and future perspectives

AU - Kuo, Tsung-Rong

AU - Chen, Chih-Hwa

PY - 2017

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N2 - Bone biomarkers included formation, resorption and regulator are released during the bone remodeling processes. These bone biomarkers have attracted much attention in the clinical assessment of osteoporosis treatment in the past decade. Combination with the measurement of bone mineral density, the clinical applications of bone biomarkers have provided comprehensive information for diagnosis of osteoporosis. However, the analytical approaches of the bone biomarkers are still the challenge for further clinical trials. In this mini-review, we have introduced the functions of bone biomarkers and then recently developed techniques for bone biomarker measurements have been systematically integrated to discuss the possibility for osteoporosis assessment in the early stage.

AB - Bone biomarkers included formation, resorption and regulator are released during the bone remodeling processes. These bone biomarkers have attracted much attention in the clinical assessment of osteoporosis treatment in the past decade. Combination with the measurement of bone mineral density, the clinical applications of bone biomarkers have provided comprehensive information for diagnosis of osteoporosis. However, the analytical approaches of the bone biomarkers are still the challenge for further clinical trials. In this mini-review, we have introduced the functions of bone biomarkers and then recently developed techniques for bone biomarker measurements have been systematically integrated to discuss the possibility for osteoporosis assessment in the early stage.

U2 - 10.1186/s40364-017-0097-4

DO - 10.1186/s40364-017-0097-4

M3 - Review article

VL - 5

SP - 18

JO - Biomarker Research

JF - Biomarker Research

SN - 2050-7771

ER -