Body mass index and outcome of acute myocardial infarction - Is there an obesity paradox?

Chin Chang Cheng, Wei Chun Huang, Kuan Rau Chiou, Feng Yu Kuo, Cheng Hung Chiang, Jin Shiou Yang, Ko Long Lin, Shin Hung Hsiao, Hwong Ru Hwang, Guang Yuan Mar, Shoa Lin Lin, Chuen Wang Chiou, Chun Peng Liu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Although there have been some studies focusing on the relationship between body mass index (BMI), coronary artery disease (CAD) and acute coronary syndrome, the clinical effects of BMI on outcomes after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) are not well known in a Taiwanese population. Methods: From January 2005 to December 2011, 1298 AMI patients who received PCI were enrolled from a single center in Taiwan. The patients were divided into 4 groups according to their BMI: underweight (BMI < 18.5 kg/m2); normal weight (18.5 ≦ BMI < 24 kg/m2); overweight (24 ≦ BMI < 27 kg/m2) and obese (BMI ≧ 27). All patients had been followed up for at least 12months, and 30-day and 5-year all-cause and cardiovascular-cause mortality were compared among the study groups. Results: The patients in the underweight group had a lower 30-day survival rate than the other 3 groups, and the underweight and normal weight patients had a lower 5-year survival rate than the overweight and obese patients. The multivariate regression analysis showed that Killip class≧2, non-use of statin, older age, hemoglobin < 12 g/dl and chronic kidney disease, but not BMI, are independent predictors of all-cause mortality. Conclusions: In this present study, the major factors affecting long-term survival are lack of using statin and older age, but not obese paradox.

Original languageEnglish
Pages (from-to)413-420
Number of pages8
JournalActa Cardiologica Sinica
Volume29
Issue number5
Publication statusPublished - Sep 1 2013
Externally publishedYes

Fingerprint

Body Mass Index
Obesity
Myocardial Infarction
Thinness
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Percutaneous Coronary Intervention
Survival Rate
Weights and Measures
Mortality
Acute Coronary Syndrome
Taiwan
Chronic Renal Insufficiency
Coronary Artery Disease
Hemoglobins
Multivariate Analysis
Regression Analysis
Survival
Population

Keywords

  • Acute myocardial infarction
  • Mortality
  • Obesity
  • Percutaneous coronary intervention
  • Survival

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Cheng, C. C., Huang, W. C., Chiou, K. R., Kuo, F. Y., Chiang, C. H., Yang, J. S., ... Liu, C. P. (2013). Body mass index and outcome of acute myocardial infarction - Is there an obesity paradox? Acta Cardiologica Sinica, 29(5), 413-420.

Body mass index and outcome of acute myocardial infarction - Is there an obesity paradox? / Cheng, Chin Chang; Huang, Wei Chun; Chiou, Kuan Rau; Kuo, Feng Yu; Chiang, Cheng Hung; Yang, Jin Shiou; Lin, Ko Long; Hsiao, Shin Hung; Hwang, Hwong Ru; Mar, Guang Yuan; Lin, Shoa Lin; Chiou, Chuen Wang; Liu, Chun Peng.

In: Acta Cardiologica Sinica, Vol. 29, No. 5, 01.09.2013, p. 413-420.

Research output: Contribution to journalArticle

Cheng, CC, Huang, WC, Chiou, KR, Kuo, FY, Chiang, CH, Yang, JS, Lin, KL, Hsiao, SH, Hwang, HR, Mar, GY, Lin, SL, Chiou, CW & Liu, CP 2013, 'Body mass index and outcome of acute myocardial infarction - Is there an obesity paradox?', Acta Cardiologica Sinica, vol. 29, no. 5, pp. 413-420.
Cheng CC, Huang WC, Chiou KR, Kuo FY, Chiang CH, Yang JS et al. Body mass index and outcome of acute myocardial infarction - Is there an obesity paradox? Acta Cardiologica Sinica. 2013 Sep 1;29(5):413-420.
Cheng, Chin Chang ; Huang, Wei Chun ; Chiou, Kuan Rau ; Kuo, Feng Yu ; Chiang, Cheng Hung ; Yang, Jin Shiou ; Lin, Ko Long ; Hsiao, Shin Hung ; Hwang, Hwong Ru ; Mar, Guang Yuan ; Lin, Shoa Lin ; Chiou, Chuen Wang ; Liu, Chun Peng. / Body mass index and outcome of acute myocardial infarction - Is there an obesity paradox?. In: Acta Cardiologica Sinica. 2013 ; Vol. 29, No. 5. pp. 413-420.
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AU - Hsiao, Shin Hung

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