Blastocyst morphology score as an indicator of embryo competence for women aged younger than 38 years in invitro fertilization cycles

Tsung Hsien Lee, Chin Der Chen, Ming Yih Wu, Hsin Fu Chen, Shee Uan Chen, Hong Nerng Ho, Yu Shih Yang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in invitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated. The relevance of blastocyst scores and female age to pregnancy outcome was assessed by logistic regression analysis. Results: We revealed that, for patients aged<35 years, the score of the best embryo was the sole factor related to multiple pregnancy, whereas the score of the best two embryos was the only factor relevant to pregnancy. For patients aged 35-37 years, the score of the best three embryos was the sole factor correlated to both pregnancy and multiple pregnancy. As for older patients, the correlation between blastocyst morphology and pregnancy outcome was mainly affected by female age. Conclusion: The blastocyst score could be used to determine the number of blastocysts transferred to younger patients, but it is less useful for patients aged > 38 years. For older patients, female age is a better indicator to determine the number of transferred blastocysts.

Original languageEnglish
Pages (from-to)374-380
Number of pages7
JournalTaiwanese Journal of Obstetrics and Gynecology
Volume52
Issue number3
DOIs
Publication statusPublished - Sep 1 2013
Externally publishedYes

Fingerprint

Blastocyst
Fertilization
Mental Competency
Embryonic Structures
Embryo Transfer
Pregnancy Outcome
Logistic Models
Regression Analysis

Keywords

  • Age
  • Blastocyst
  • Invitro fertilization
  • Multiple gestation
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Blastocyst morphology score as an indicator of embryo competence for women aged younger than 38 years in invitro fertilization cycles. / Lee, Tsung Hsien; Chen, Chin Der; Wu, Ming Yih; Chen, Hsin Fu; Chen, Shee Uan; Ho, Hong Nerng; Yang, Yu Shih.

In: Taiwanese Journal of Obstetrics and Gynecology, Vol. 52, No. 3, 01.09.2013, p. 374-380.

Research output: Contribution to journalArticle

Lee, Tsung Hsien ; Chen, Chin Der ; Wu, Ming Yih ; Chen, Hsin Fu ; Chen, Shee Uan ; Ho, Hong Nerng ; Yang, Yu Shih. / Blastocyst morphology score as an indicator of embryo competence for women aged younger than 38 years in invitro fertilization cycles. In: Taiwanese Journal of Obstetrics and Gynecology. 2013 ; Vol. 52, No. 3. pp. 374-380.
@article{6da0ba0c66d9450fabdc197abab051f8,
title = "Blastocyst morphology score as an indicator of embryo competence for women aged younger than 38 years in invitro fertilization cycles",
abstract = "Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in invitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated. The relevance of blastocyst scores and female age to pregnancy outcome was assessed by logistic regression analysis. Results: We revealed that, for patients aged<35 years, the score of the best embryo was the sole factor related to multiple pregnancy, whereas the score of the best two embryos was the only factor relevant to pregnancy. For patients aged 35-37 years, the score of the best three embryos was the sole factor correlated to both pregnancy and multiple pregnancy. As for older patients, the correlation between blastocyst morphology and pregnancy outcome was mainly affected by female age. Conclusion: The blastocyst score could be used to determine the number of blastocysts transferred to younger patients, but it is less useful for patients aged > 38 years. For older patients, female age is a better indicator to determine the number of transferred blastocysts.",
keywords = "Age, Blastocyst, Invitro fertilization, Multiple gestation, Pregnancy",
author = "Lee, {Tsung Hsien} and Chen, {Chin Der} and Wu, {Ming Yih} and Chen, {Hsin Fu} and Chen, {Shee Uan} and Ho, {Hong Nerng} and Yang, {Yu Shih}",
year = "2013",
month = "9",
day = "1",
doi = "10.1016/j.tjog.2012.01.038",
language = "English",
volume = "52",
pages = "374--380",
journal = "Taiwanese Journal of Obstetrics and Gynecology",
issn = "1028-4559",
publisher = "臺灣婦產科醫學會",
number = "3",

}

TY - JOUR

T1 - Blastocyst morphology score as an indicator of embryo competence for women aged younger than 38 years in invitro fertilization cycles

AU - Lee, Tsung Hsien

AU - Chen, Chin Der

AU - Wu, Ming Yih

AU - Chen, Hsin Fu

AU - Chen, Shee Uan

AU - Ho, Hong Nerng

AU - Yang, Yu Shih

PY - 2013/9/1

Y1 - 2013/9/1

N2 - Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in invitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated. The relevance of blastocyst scores and female age to pregnancy outcome was assessed by logistic regression analysis. Results: We revealed that, for patients aged<35 years, the score of the best embryo was the sole factor related to multiple pregnancy, whereas the score of the best two embryos was the only factor relevant to pregnancy. For patients aged 35-37 years, the score of the best three embryos was the sole factor correlated to both pregnancy and multiple pregnancy. As for older patients, the correlation between blastocyst morphology and pregnancy outcome was mainly affected by female age. Conclusion: The blastocyst score could be used to determine the number of blastocysts transferred to younger patients, but it is less useful for patients aged > 38 years. For older patients, female age is a better indicator to determine the number of transferred blastocysts.

AB - Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in invitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated. The relevance of blastocyst scores and female age to pregnancy outcome was assessed by logistic regression analysis. Results: We revealed that, for patients aged<35 years, the score of the best embryo was the sole factor related to multiple pregnancy, whereas the score of the best two embryos was the only factor relevant to pregnancy. For patients aged 35-37 years, the score of the best three embryos was the sole factor correlated to both pregnancy and multiple pregnancy. As for older patients, the correlation between blastocyst morphology and pregnancy outcome was mainly affected by female age. Conclusion: The blastocyst score could be used to determine the number of blastocysts transferred to younger patients, but it is less useful for patients aged > 38 years. For older patients, female age is a better indicator to determine the number of transferred blastocysts.

KW - Age

KW - Blastocyst

KW - Invitro fertilization

KW - Multiple gestation

KW - Pregnancy

UR - http://www.scopus.com/inward/record.url?scp=84884590641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84884590641&partnerID=8YFLogxK

U2 - 10.1016/j.tjog.2012.01.038

DO - 10.1016/j.tjog.2012.01.038

M3 - Article

C2 - 24075376

AN - SCOPUS:84884590641

VL - 52

SP - 374

EP - 380

JO - Taiwanese Journal of Obstetrics and Gynecology

JF - Taiwanese Journal of Obstetrics and Gynecology

SN - 1028-4559

IS - 3

ER -