Abstract
Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in invitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated. The relevance of blastocyst scores and female age to pregnancy outcome was assessed by logistic regression analysis. Results: We revealed that, for patients aged<35 years, the score of the best embryo was the sole factor related to multiple pregnancy, whereas the score of the best two embryos was the only factor relevant to pregnancy. For patients aged 35-37 years, the score of the best three embryos was the sole factor correlated to both pregnancy and multiple pregnancy. As for older patients, the correlation between blastocyst morphology and pregnancy outcome was mainly affected by female age. Conclusion: The blastocyst score could be used to determine the number of blastocysts transferred to younger patients, but it is less useful for patients aged > 38 years. For older patients, female age is a better indicator to determine the number of transferred blastocysts.
| Original language | English |
|---|---|
| Pages (from-to) | 374-380 |
| Number of pages | 7 |
| Journal | Taiwanese Journal of Obstetrics and Gynecology |
| Volume | 52 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 1 2013 |
| Externally published | Yes |
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Keywords
- Age
- Blastocyst
- Invitro fertilization
- Multiple gestation
- Pregnancy
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Blastocyst morphology score as an indicator of embryo competence for women aged younger than 38 years in invitro fertilization cycles. / Lee, Tsung Hsien; Chen, Chin Der; Wu, Ming Yih; Chen, Hsin Fu; Chen, Shee Uan; Ho, Hong Nerng; Yang, Yu Shih.
In: Taiwanese Journal of Obstetrics and Gynecology, Vol. 52, No. 3, 01.09.2013, p. 374-380.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Blastocyst morphology score as an indicator of embryo competence for women aged younger than 38 years in invitro fertilization cycles
AU - Lee, Tsung Hsien
AU - Chen, Chin Der
AU - Wu, Ming Yih
AU - Chen, Hsin Fu
AU - Chen, Shee Uan
AU - Ho, Hong Nerng
AU - Yang, Yu Shih
PY - 2013/9/1
Y1 - 2013/9/1
N2 - Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in invitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated. The relevance of blastocyst scores and female age to pregnancy outcome was assessed by logistic regression analysis. Results: We revealed that, for patients aged<35 years, the score of the best embryo was the sole factor related to multiple pregnancy, whereas the score of the best two embryos was the only factor relevant to pregnancy. For patients aged 35-37 years, the score of the best three embryos was the sole factor correlated to both pregnancy and multiple pregnancy. As for older patients, the correlation between blastocyst morphology and pregnancy outcome was mainly affected by female age. Conclusion: The blastocyst score could be used to determine the number of blastocysts transferred to younger patients, but it is less useful for patients aged > 38 years. For older patients, female age is a better indicator to determine the number of transferred blastocysts.
AB - Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in invitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated. The relevance of blastocyst scores and female age to pregnancy outcome was assessed by logistic regression analysis. Results: We revealed that, for patients aged<35 years, the score of the best embryo was the sole factor related to multiple pregnancy, whereas the score of the best two embryos was the only factor relevant to pregnancy. For patients aged 35-37 years, the score of the best three embryos was the sole factor correlated to both pregnancy and multiple pregnancy. As for older patients, the correlation between blastocyst morphology and pregnancy outcome was mainly affected by female age. Conclusion: The blastocyst score could be used to determine the number of blastocysts transferred to younger patients, but it is less useful for patients aged > 38 years. For older patients, female age is a better indicator to determine the number of transferred blastocysts.
KW - Age
KW - Blastocyst
KW - Invitro fertilization
KW - Multiple gestation
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=84884590641&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884590641&partnerID=8YFLogxK
U2 - 10.1016/j.tjog.2012.01.038
DO - 10.1016/j.tjog.2012.01.038
M3 - Article
C2 - 24075376
AN - SCOPUS:84884590641
VL - 52
SP - 374
EP - 380
JO - Taiwanese Journal of Obstetrics and Gynecology
JF - Taiwanese Journal of Obstetrics and Gynecology
SN - 1028-4559
IS - 3
ER -