Biosynthesis, production and applications of bacterial cellulose

Shin Ping Lin, Iris Loira Calvar, Jeffrey M. Catchmark, Je Ruei Liu, Ali Demirci, Kuan Chen Cheng

Research output: Contribution to journalReview articlepeer-review

315 Citations (Scopus)


Bacterial cellulose (BC) as a never-dried biopolymer synthesized in abundance by Gluconacetobacter xylinus is in a pure form which requires no intensive processing to remove unwanted impurities and contaminants such as lignin, pectin and hemicellulose. In contrast to plant cellulose, BC, with several remarkable physical properties, can be grown to any desired shape and structure to meet the needs of different applications. BC has been commercialized as diet foods, filtration membranes, paper additives, and wound dressings. This review article presents an overview of BC structure, biosynthesis, applications, state-of-the-art advances in enhancing BC production, and its material properties through the investigations of genetic regulations, fermentation parameters, and bioreactor design. In addition, future prospects on its applications through chemical modification as a new biologically active derivative will be discussed.

Original languageEnglish
Pages (from-to)2191-2219
Number of pages29
Issue number5
Publication statusPublished - Oct 1 2013
Externally publishedYes


  • Bacterial cellulose
  • Biosynthesis
  • Cellulose application
  • Cellulose modification
  • Cellulose production
  • Gluconacetobacter xylinus

ASJC Scopus subject areas

  • Polymers and Plastics


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