Biomonitoring of alkylphenols exposure for textile and housekeeping workers

Mei Lien Chen, Wan Ping Lee, Hsin Y. Chung, Bey Rong Guo, I. Fang Mao

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

4-Nonylphenols (NP), 4- tert -ocytylphenols (OP), and 2,4-di- tert -butylphenols (BP) are ubiquitous in daily foodstuffs. These alkylphenols are widely used in industry, and NP and OP are endocrine disruptors. This study involved biomonitoring of the alkylphenols in plasma and urine from textile and housekeeping workers. The objective was to measure the internal level of alkylphenols and clarify the occupational exposure of alkylphenols for these two working groups. Forty textile workers and 33 housekeeping workers were recruited in this study. Urine and plasma samples were enzymatic deconjugation, followed by cleanup with solid-phase extraction. After extraction, the samples were analysed with reverse-phase high-performance liquid chromatography coupled with fluorescence detection. The method was validated with the recovery and reproducibility test. The measurement results demonstrated apparent occupational exposure, since the urinary alkylphenols were significantly higher in the end-of-shift samples, 42.06plusmn;46.63 ng/mL, than in the preshift samples, 23.50±17.34 ng/mL, for the textile exposed workers. Meanwhile, the three kinds of alkylphenols were commonly detected in the biological samples. The plasma concentrations were higher than the urine concentrations. The average plasma concentrations of NP, OP, and BP were 53.21±49.74, 16.02±2.81, and 25.83±7.10 ng/g for the housekeeping workers and 6.25±4.83, 6.52±8.67, and 6.47±13.34 ng/mL in urine, respectively. The results of this study suggest that multiple exposure routes, including dietary intake, inhalation, and skin absorption, might contribute to the internal alkylphenol dose. The potential adverse effects caused by exposure of occupational workers is concerned.

Original languageEnglish
Pages (from-to)335-347
Number of pages13
JournalInternational Journal of Environmental Analytical Chemistry
Volume85
Issue number4-5
DOIs
Publication statusPublished - Apr 2005

Fingerprint

Housekeeping
Textiles
Environmental Monitoring
biomonitoring
urine
occupational exposure
Occupational Exposure
Urine
Plasmas
plasma
2,4-di-tert-butylphenol
textile workers
Skin Absorption
Endocrine Disruptors
sampling
endocrine disruptor
Solid Phase Extraction
High performance liquid chromatography
Reverse-Phase Chromatography
exposure pathways

Keywords

  • Biomonitoring
  • Endocrine disruptor
  • Nonylphenols

ASJC Scopus subject areas

  • Analytical Chemistry
  • Environmental Science(all)
  • Environmental Chemistry

Cite this

Biomonitoring of alkylphenols exposure for textile and housekeeping workers. / Chen, Mei Lien; Lee, Wan Ping; Chung, Hsin Y.; Guo, Bey Rong; Mao, I. Fang.

In: International Journal of Environmental Analytical Chemistry, Vol. 85, No. 4-5, 04.2005, p. 335-347.

Research output: Contribution to journalArticle

Chen, Mei Lien ; Lee, Wan Ping ; Chung, Hsin Y. ; Guo, Bey Rong ; Mao, I. Fang. / Biomonitoring of alkylphenols exposure for textile and housekeeping workers. In: International Journal of Environmental Analytical Chemistry. 2005 ; Vol. 85, No. 4-5. pp. 335-347.
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