Biomedical electrosurgery devices containing nanostructure for minimally invasive surgery: reduction of thermal injury and acceleration of wound healing for liver cancer

Wen Tien Hsiao, Li-Hsiang Lin, Hsi Jen Chiang, Keng-Liang Ou, Han-Yi Cheng

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The aim of the present study was to investigate the thermal injury in the liver after a minimally invasive electrosurgery technique with a copper-doped diamond-like carbon (DLC-Cu) surface coating. To effectively utilize electrosurgery in a clinical caner setting, it is necessary to suppress the thermal injury to adjacent tissues. The surface morphologies of DLC-Cu thin films were characterized using scanning electron microscopy and transmission electron microscopy. Three-dimensional liver models were reconstructed using magnetic resonance imaging to simulate the electrosurgical procedure. Our results indicated that the temperature decreased significantly when minimally electrosurgery with nanostructured DLC-Cu thin films was used, and that it continued to decrease with increasing film thickness. In an animal model, thermography revealed that the surgical temperature was significantly lower in the minimally invasive electrosurgery with DLC-Cu thin film (DLC-Cu-SS) compared to untreated electrosurgery. In addition, DLC-Cu-SS created a relatively small thermal injury area and lateral thermal effect. These results indicated that the biomedical nanostructure coating reduced excessive thermal injury, and uniformly distributed temperature in the liver.
Original languageEnglish
Pages (from-to)1-9
Number of pages9
JournalJournal of materials science. Materials in medicine
Volume26
Issue number2
DOIs
Publication statusPublished - 2015

Fingerprint

Electrosurgery
Minimally Invasive Surgical Procedures
Nanostructures
Liver Neoplasms
Liver
Wound Healing
Surgery
Hot Temperature
Equipment and Supplies
Wounds and Injuries
Thin films
Temperature
Coatings
Diamond
Magnetic resonance
Transmission Electron Microscopy
Electron Scanning Microscopy
Thermal effects
Surface morphology
Film thickness

ASJC Scopus subject areas

  • Biophysics
  • Biomaterials
  • Bioengineering
  • Biomedical Engineering

Cite this

Biomedical electrosurgery devices containing nanostructure for minimally invasive surgery : reduction of thermal injury and acceleration of wound healing for liver cancer. / Hsiao, Wen Tien; Lin, Li-Hsiang; Chiang, Hsi Jen; Ou, Keng-Liang; Cheng, Han-Yi.

In: Journal of materials science. Materials in medicine, Vol. 26, No. 2, 2015, p. 1-9.

Research output: Contribution to journalArticle

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