Abstract

Gold nanoclusters (AuNCs) have been extensively applied as a fluorescent probe for biomedical applications in imaging, detection, and therapy due to their unique chemical and physical properties. Fluorescent probes of AuNCs have exhibited high compatibility, superior photostablility, and excellent water solubility which resulted in remarkable biomedical applications for long-term imaging, high-sensitivity detection, and target-specific treatment. Recently, great efforts have been made in the developments of AuNCs as the fluorescent probes for various biomedical applications. In this review, we have collected fluorescent AuNCs prepared by different ligands, including small molecules, polymers, and biomacromolecules, and highlighted current achievements of AuNCs in biomedical applications for imaging, detection, and therapy. According to these advances, we further provided conclusions of present challenges and future perspectives of AuNCs for fundamental investigations and practical biomedical applications.

Original languageEnglish
Article number302
JournalNanoscale Research Letters
Volume13
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Nanoclusters
nanoclusters
Gold
gold
Fluorescent Dyes
Imaging techniques
probes
therapy
chemical properties
Chemical properties
compatibility
Polymers
solubility
Solubility
Physical properties
physical properties
Ligands
ligands
Molecules
Water

Keywords

  • Biomacromolecules
  • Detection
  • Gold nanoclusters
  • Imaging
  • Polymers
  • Small molecules
  • Therapy; ligand

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics

Cite this

Biomedical Applications for Gold Nanoclusters : Recent Developments and Future Perspectives. / Kaur, Navdeep; Aditya, Robby Nur; Singh, Arshdeep; Kuo, Tsung Rong.

In: Nanoscale Research Letters, Vol. 13, 302, 01.01.2018.

Research output: Contribution to journalReview article

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N2 - Gold nanoclusters (AuNCs) have been extensively applied as a fluorescent probe for biomedical applications in imaging, detection, and therapy due to their unique chemical and physical properties. Fluorescent probes of AuNCs have exhibited high compatibility, superior photostablility, and excellent water solubility which resulted in remarkable biomedical applications for long-term imaging, high-sensitivity detection, and target-specific treatment. Recently, great efforts have been made in the developments of AuNCs as the fluorescent probes for various biomedical applications. In this review, we have collected fluorescent AuNCs prepared by different ligands, including small molecules, polymers, and biomacromolecules, and highlighted current achievements of AuNCs in biomedical applications for imaging, detection, and therapy. According to these advances, we further provided conclusions of present challenges and future perspectives of AuNCs for fundamental investigations and practical biomedical applications.

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