This study evaluated the usefulness of bioceramic materials (ceramic materials that emit high-performance far-infrared (FIR) rays), processed into fabrics using a traditional manufacturing melt spinning method. Numerous measurements were designed to test the biological functions of 1% bioceramic fabrics. These included physical induction of intracellular nitric oxide (NO) in NIH 3T3 cells (mouse fibroblasts), the effects on cell viability in osteoblastic cells (MC3T3-E1) under hydrogen peroxide-mediated oxidative stress, and the effects on lipopolysaccharide (LPS)-induced cyclo-oxygenase-2 (COX-2) and prostaglandin E2 (PGE2) production in a chondrosarcoma (SW1353) cell line. When compared to the control group, the bioceramic fabrics were capable of inducing further intracellular NO production using NIH 3T3 cells, and maintaining increased viability and against cell intoxication of osteoblastic cells by suppressing cell release of lactate dehydrogenase (LDH) under oxidative stress. In addition, it was found to suppress LPS-induced COX-2 production more significantly in a SW1353 cell line. These processes represent the biomolecular changes occurring during promotion of decline in aging, prevention of osteoporosis, and prevention of inflammatory processes within the human body. Therefore, these bioceramic fabrics are likely to fulfill their claims of having health-promoting benefits.
ASJC Scopus subject areas
- Polymers and Plastics
- Chemical Engineering (miscellaneous)