Biological correlates of psychological states among young children: a cross-sectional examination of roles of aspartate transaminase/alanine aminotransferase, insulin, and cytokines

Kuo Hsuan Chung, Chien Ming Hu, Ying Ru Chen, Hung Yi Chiou, Yi Hua Chen

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Compared to data on adolescents and adults, limited research has been conducted on biological correlates among young children with possible psychological difficulties, especially in Asian countries. By focusing on various peripheral biochemical indicators, we investigated potential biological correlates of psychological states in a community sample of Taiwanese school children aged 6–10 years. In total, 307 students (159 obese children and 148 normal-weight children) were selected from first- and fourth-grade school children in eight elementary schools in the Taipei metropolitan area in 2009. These children underwent a comprehensive health examination, including a physical examination, blood sample analysis, and questionnaire administration in a hospital. Differences in anthropometric and serum biochemical readings were compared between children with average and worse levels on each of the five psychological domains. We found that interleukin (IL)-1β [β = 1.29, 95 % confidence interval (CI) 0.50–2.09], IL-10 (β = 1.61, 95 % CI

Original languageEnglish
Pages (from-to)5102-5112
Number of pages11
JournalChinese Science Bulletin
Volume59
Issue number35
DOIs
Publication statusPublished - 2014

Fingerprint

Aspartate Aminotransferases
Alanine Transaminase
Insulin
Cytokines
Psychology
Confidence Intervals
Interleukin-1
Interleukin-10
Physical Examination
Reading
Students
Weights and Measures
Health
Serum
Research

Keywords

  • Alanine aminotransferase (ALT)
  • Anxiety
  • Aspartate transaminase (AST)
  • Depression
  • Interleukin-10
  • Interleukin-1β

ASJC Scopus subject areas

  • General

Cite this

@article{a70917ebfeef4b05a6ade409db1e22cb,
title = "Biological correlates of psychological states among young children: a cross-sectional examination of roles of aspartate transaminase/alanine aminotransferase, insulin, and cytokines",
abstract = "Compared to data on adolescents and adults, limited research has been conducted on biological correlates among young children with possible psychological difficulties, especially in Asian countries. By focusing on various peripheral biochemical indicators, we investigated potential biological correlates of psychological states in a community sample of Taiwanese school children aged 6–10 years. In total, 307 students (159 obese children and 148 normal-weight children) were selected from first- and fourth-grade school children in eight elementary schools in the Taipei metropolitan area in 2009. These children underwent a comprehensive health examination, including a physical examination, blood sample analysis, and questionnaire administration in a hospital. Differences in anthropometric and serum biochemical readings were compared between children with average and worse levels on each of the five psychological domains. We found that interleukin (IL)-1β [β = 1.29, 95 {\%} confidence interval (CI) 0.50–2.09], IL-10 (β = 1.61, 95 {\%} CI",
keywords = "Alanine aminotransferase (ALT), Anxiety, Aspartate transaminase (AST), Depression, Interleukin-10, Interleukin-1β",
author = "Chung, {Kuo Hsuan} and Hu, {Chien Ming} and Chen, {Ying Ru} and Chiou, {Hung Yi} and Chen, {Yi Hua}",
year = "2014",
doi = "10.1007/s11434-014-0617-7",
language = "English",
volume = "59",
pages = "5102--5112",
journal = "Science Bulletin",
issn = "2095-9273",
publisher = "Springer Science + Business Media",
number = "35",

}

TY - JOUR

T1 - Biological correlates of psychological states among young children

T2 - a cross-sectional examination of roles of aspartate transaminase/alanine aminotransferase, insulin, and cytokines

AU - Chung, Kuo Hsuan

AU - Hu, Chien Ming

AU - Chen, Ying Ru

AU - Chiou, Hung Yi

AU - Chen, Yi Hua

PY - 2014

Y1 - 2014

N2 - Compared to data on adolescents and adults, limited research has been conducted on biological correlates among young children with possible psychological difficulties, especially in Asian countries. By focusing on various peripheral biochemical indicators, we investigated potential biological correlates of psychological states in a community sample of Taiwanese school children aged 6–10 years. In total, 307 students (159 obese children and 148 normal-weight children) were selected from first- and fourth-grade school children in eight elementary schools in the Taipei metropolitan area in 2009. These children underwent a comprehensive health examination, including a physical examination, blood sample analysis, and questionnaire administration in a hospital. Differences in anthropometric and serum biochemical readings were compared between children with average and worse levels on each of the five psychological domains. We found that interleukin (IL)-1β [β = 1.29, 95 % confidence interval (CI) 0.50–2.09], IL-10 (β = 1.61, 95 % CI

AB - Compared to data on adolescents and adults, limited research has been conducted on biological correlates among young children with possible psychological difficulties, especially in Asian countries. By focusing on various peripheral biochemical indicators, we investigated potential biological correlates of psychological states in a community sample of Taiwanese school children aged 6–10 years. In total, 307 students (159 obese children and 148 normal-weight children) were selected from first- and fourth-grade school children in eight elementary schools in the Taipei metropolitan area in 2009. These children underwent a comprehensive health examination, including a physical examination, blood sample analysis, and questionnaire administration in a hospital. Differences in anthropometric and serum biochemical readings were compared between children with average and worse levels on each of the five psychological domains. We found that interleukin (IL)-1β [β = 1.29, 95 % confidence interval (CI) 0.50–2.09], IL-10 (β = 1.61, 95 % CI

KW - Alanine aminotransferase (ALT)

KW - Anxiety

KW - Aspartate transaminase (AST)

KW - Depression

KW - Interleukin-10

KW - Interleukin-1β

UR - http://www.scopus.com/inward/record.url?scp=84922079301&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922079301&partnerID=8YFLogxK

U2 - 10.1007/s11434-014-0617-7

DO - 10.1007/s11434-014-0617-7

M3 - Article

AN - SCOPUS:84922079301

VL - 59

SP - 5102

EP - 5112

JO - Science Bulletin

JF - Science Bulletin

SN - 2095-9273

IS - 35

ER -