Biliary complications and management in pediatric living donor liver transplantation for underlying biliary atresia

C. H. Lu, L. L.C. Tsang, T. L. Huang, T. Y. Chen, H. Y. Ou, C. Y. Yu, C. L. Chen, Y. F. Cheng

Research output: Contribution to journalArticle

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Abstract

Background: Biliary complications are a major problem in pediatric liver transplantation. The aim of this study was to evaluate the management and outcomes of biliary complication after pediatric living donor liver transplantation (LDLT). Methods: From 1994 to 2010, 157 pediatric LDLT due to biliary atresia were performed in our center. Doppler ultrasound was initially performed daily for 2 weeks postoperatively to evaluate biliary and vascular complications. Computed tomography and or magnetic resonance cholangiography were performed when complications were suspected. They were treated using radiological or surgical interventions. Results: Among the 157 cases, we observed 10 (6.3%) biliary complications, which were divided into three groups: bile leakage (n = 3); biliary stricture without vascular complication (n = 4); and biliary stricture with vascular complication (n = 3). The three cases bile leakages recovered after interventional procedures. The seven biliary strictures underwent percutaneous transhepatic cholangial drainage (PTCD). All cases without vascular complications were completely cured after PTCD or a subsequent surgical re-anastomosis. In the vascular complication group, early recorrection of the HA occlusion with successful PTCD treatment were performed in two cases, but one other case with diffuse ischemic biliary destruction had a poor result. Conclusion: Successful interventional radiographic approaches are effective for anastomotic biliary complications but with poor results in diffuse ischemic biliary destruction.

Original languageEnglish
Pages (from-to)476-477
Number of pages2
JournalTransplantation Proceedings
Volume44
Issue number2
DOIs
Publication statusPublished - Mar 1 2012

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Biliary Atresia
Living Donors
Liver Transplantation
Blood Vessels
Pediatrics
Drainage
Pathologic Constriction
Bile
Surgical Anastomosis
Doppler Ultrasonography
Cholangiography
Magnetic Resonance Spectroscopy
Tomography

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Biliary complications and management in pediatric living donor liver transplantation for underlying biliary atresia. / Lu, C. H.; Tsang, L. L.C.; Huang, T. L.; Chen, T. Y.; Ou, H. Y.; Yu, C. Y.; Chen, C. L.; Cheng, Y. F.

In: Transplantation Proceedings, Vol. 44, No. 2, 01.03.2012, p. 476-477.

Research output: Contribution to journalArticle

Lu, C. H. ; Tsang, L. L.C. ; Huang, T. L. ; Chen, T. Y. ; Ou, H. Y. ; Yu, C. Y. ; Chen, C. L. ; Cheng, Y. F. / Biliary complications and management in pediatric living donor liver transplantation for underlying biliary atresia. In: Transplantation Proceedings. 2012 ; Vol. 44, No. 2. pp. 476-477.
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