Basal FSH level changes after different types of uterine vessel occlusion in the management of uterine fibroids

Wen Ling Lee, Wei Min Liu, Jong Ling Fuh, Ying Chieh Tsai, Chun Che Shih, Peng Hui Wang

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Objective: To assess the effect on FSH of the application of different types of uterine vessel blockage (uterine artery occlusion alone [UAO] or with blockage of vessel anastomosis [UVO]) in the management of women with fibroids. Design: Case-control study. Setting: Medical center. Patient(s): One hundred ten women with uterine fibroids. Intervention(s): Forty-four consecutive patients undergoing UAO were compared with 66 matched subjects who underwent UVO during the same period. Main Outcome Measure(s): Surgery types and FSH levels were compared. Result(s): At the first month after surgery, FSH levels were elevated from 5.5 mIU/mL to 14.2 and 8.7 mIU/mL in the UVO and UAO groups, respectively. The difference between the 2 groups continued up to 6 months and disappeared thereafter. More patients (38%) in the UVO group had an increased FSH level of >10 mIU/mL, compared with 5% in the UAO group at the first month after surgery, which contributed to the high percentage of women with irregular menstruation. Conclusion(s): Women treated with UVO were associated with a greater risk of a significant increase in FSH level at the first month after operation than those treated with UAO, which may be a reflection of diminished ovarian function. The long-term effect was uncertain, because of the lack of difference in the FSH levels between the two groups.

Original languageEnglish
Pages (from-to)2286-2290
Number of pages5
JournalFertility and Sterility
Volume94
Issue number6
DOIs
Publication statusPublished - Nov 2010

Fingerprint

Uterine Artery
Leiomyoma
Menstruation
Case-Control Studies
Outcome Assessment (Health Care)

Keywords

  • Fibroids
  • follicle-stimulating hormone
  • laparoscopic uterine vessel occlusion
  • leiomyomas
  • menstrual cycle

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Basal FSH level changes after different types of uterine vessel occlusion in the management of uterine fibroids. / Lee, Wen Ling; Liu, Wei Min; Fuh, Jong Ling; Tsai, Ying Chieh; Shih, Chun Che; Wang, Peng Hui.

In: Fertility and Sterility, Vol. 94, No. 6, 11.2010, p. 2286-2290.

Research output: Contribution to journalArticle

Lee, Wen Ling ; Liu, Wei Min ; Fuh, Jong Ling ; Tsai, Ying Chieh ; Shih, Chun Che ; Wang, Peng Hui. / Basal FSH level changes after different types of uterine vessel occlusion in the management of uterine fibroids. In: Fertility and Sterility. 2010 ; Vol. 94, No. 6. pp. 2286-2290.
@article{f1310dc2f779447fbfc829563c1942f1,
title = "Basal FSH level changes after different types of uterine vessel occlusion in the management of uterine fibroids",
abstract = "Objective: To assess the effect on FSH of the application of different types of uterine vessel blockage (uterine artery occlusion alone [UAO] or with blockage of vessel anastomosis [UVO]) in the management of women with fibroids. Design: Case-control study. Setting: Medical center. Patient(s): One hundred ten women with uterine fibroids. Intervention(s): Forty-four consecutive patients undergoing UAO were compared with 66 matched subjects who underwent UVO during the same period. Main Outcome Measure(s): Surgery types and FSH levels were compared. Result(s): At the first month after surgery, FSH levels were elevated from 5.5 mIU/mL to 14.2 and 8.7 mIU/mL in the UVO and UAO groups, respectively. The difference between the 2 groups continued up to 6 months and disappeared thereafter. More patients (38{\%}) in the UVO group had an increased FSH level of >10 mIU/mL, compared with 5{\%} in the UAO group at the first month after surgery, which contributed to the high percentage of women with irregular menstruation. Conclusion(s): Women treated with UVO were associated with a greater risk of a significant increase in FSH level at the first month after operation than those treated with UAO, which may be a reflection of diminished ovarian function. The long-term effect was uncertain, because of the lack of difference in the FSH levels between the two groups.",
keywords = "Fibroids, follicle-stimulating hormone, laparoscopic uterine vessel occlusion, leiomyomas, menstrual cycle",
author = "Lee, {Wen Ling} and Liu, {Wei Min} and Fuh, {Jong Ling} and Tsai, {Ying Chieh} and Shih, {Chun Che} and Wang, {Peng Hui}",
year = "2010",
month = "11",
doi = "10.1016/j.fertnstert.2009.11.038",
language = "English",
volume = "94",
pages = "2286--2290",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier",
number = "6",

}

TY - JOUR

T1 - Basal FSH level changes after different types of uterine vessel occlusion in the management of uterine fibroids

AU - Lee, Wen Ling

AU - Liu, Wei Min

AU - Fuh, Jong Ling

AU - Tsai, Ying Chieh

AU - Shih, Chun Che

AU - Wang, Peng Hui

PY - 2010/11

Y1 - 2010/11

N2 - Objective: To assess the effect on FSH of the application of different types of uterine vessel blockage (uterine artery occlusion alone [UAO] or with blockage of vessel anastomosis [UVO]) in the management of women with fibroids. Design: Case-control study. Setting: Medical center. Patient(s): One hundred ten women with uterine fibroids. Intervention(s): Forty-four consecutive patients undergoing UAO were compared with 66 matched subjects who underwent UVO during the same period. Main Outcome Measure(s): Surgery types and FSH levels were compared. Result(s): At the first month after surgery, FSH levels were elevated from 5.5 mIU/mL to 14.2 and 8.7 mIU/mL in the UVO and UAO groups, respectively. The difference between the 2 groups continued up to 6 months and disappeared thereafter. More patients (38%) in the UVO group had an increased FSH level of >10 mIU/mL, compared with 5% in the UAO group at the first month after surgery, which contributed to the high percentage of women with irregular menstruation. Conclusion(s): Women treated with UVO were associated with a greater risk of a significant increase in FSH level at the first month after operation than those treated with UAO, which may be a reflection of diminished ovarian function. The long-term effect was uncertain, because of the lack of difference in the FSH levels between the two groups.

AB - Objective: To assess the effect on FSH of the application of different types of uterine vessel blockage (uterine artery occlusion alone [UAO] or with blockage of vessel anastomosis [UVO]) in the management of women with fibroids. Design: Case-control study. Setting: Medical center. Patient(s): One hundred ten women with uterine fibroids. Intervention(s): Forty-four consecutive patients undergoing UAO were compared with 66 matched subjects who underwent UVO during the same period. Main Outcome Measure(s): Surgery types and FSH levels were compared. Result(s): At the first month after surgery, FSH levels were elevated from 5.5 mIU/mL to 14.2 and 8.7 mIU/mL in the UVO and UAO groups, respectively. The difference between the 2 groups continued up to 6 months and disappeared thereafter. More patients (38%) in the UVO group had an increased FSH level of >10 mIU/mL, compared with 5% in the UAO group at the first month after surgery, which contributed to the high percentage of women with irregular menstruation. Conclusion(s): Women treated with UVO were associated with a greater risk of a significant increase in FSH level at the first month after operation than those treated with UAO, which may be a reflection of diminished ovarian function. The long-term effect was uncertain, because of the lack of difference in the FSH levels between the two groups.

KW - Fibroids

KW - follicle-stimulating hormone

KW - laparoscopic uterine vessel occlusion

KW - leiomyomas

KW - menstrual cycle

UR - http://www.scopus.com/inward/record.url?scp=77954642768&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954642768&partnerID=8YFLogxK

U2 - 10.1016/j.fertnstert.2009.11.038

DO - 10.1016/j.fertnstert.2009.11.038

M3 - Article

C2 - 20056209

AN - SCOPUS:77954642768

VL - 94

SP - 2286

EP - 2290

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 6

ER -