Bacteriological Efficacy of Nafcillin and Vancomycin Alone or Combined with Rifampicin or Amikacin in Experimental Meningitis Due to Methicillin-Susceptible or -Resistant Staphylococcus Aureus

Koichiro Sato, Tzou Yien Lin, Leah Weintrub, Kurt Olsen, George H. McCracken

Research output: Contribution to journalArticle

8 Citations (Scopus)


Although meningitis due to Staphylococcus aureus is uncommon today in infants and children, it remains an important pathogen1), particularly in catheter-associated infections. In cerebrospinal fluid (CSF) shunt infections, S. aureus accounts for approximately one quarter of infections2,3) Optimal antimicrobial therapy of that infection and of other infections of the central nervous system due to S, aureus is problematic, particularly for disease due to methicillin (DMPPC)-resistant strains4, 5).

Original languageEnglish
Pages (from-to)2155-2162
Number of pages8
JournalJapanese Journal of Antibiotics
Issue number8
Publication statusPublished - 1985
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)
  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

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