Autoimmune hepatitis with raised alpha-fetoprotein level as the presenting symptoms of systemic lupus erythematosus: A case report

Feng Cheng Liu, Deh Ming Chang, Jenn Haung Lai, Chih Kung Lin, Hsiang Cheng Chen, Tsung Y. Hou, San Yuan Kuo

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Systemic lupus erythematosus (SLE) and autoimmune hepatitis are distinct clinical disorders, which rarely occur, in the same patient. We describe a 59-year-old woman with coexistence of both conditions. Photosensitivity, arthritis, positive ANA, and extreme elevation of anti-dsDNA concluded the diagnosis of SLE. Hyperbilirubinemia, high serum value of liver function, and elevation of alpha-fetoprotein were also prominent. By a review of pertinent literature, clinical investigation, calculation of autoimmune hepatitis score, and pathology of liver biopsy specimen, we were in favor of autoimmune hepatitis. Awareness of this rare presentation may be beneficial to clinicians in identifying and treating patients with both SLE and autoimmune hepatitis.

Original languageEnglish
Pages (from-to)489-491
Number of pages3
JournalRheumatology International
Volume27
Issue number5
DOIs
Publication statusPublished - Mar 1 2007
Externally publishedYes

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Autoimmune Hepatitis
alpha-Fetoproteins
Systemic Lupus Erythematosus
Hyperbilirubinemia
Liver
Arthritis
Pathology
Biopsy
Serum

Keywords

  • Autoimmune hepatitis
  • Lupus hepatitis
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology

Cite this

Autoimmune hepatitis with raised alpha-fetoprotein level as the presenting symptoms of systemic lupus erythematosus : A case report. / Liu, Feng Cheng; Chang, Deh Ming; Lai, Jenn Haung; Lin, Chih Kung; Chen, Hsiang Cheng; Hou, Tsung Y.; Kuo, San Yuan.

In: Rheumatology International, Vol. 27, No. 5, 01.03.2007, p. 489-491.

Research output: Contribution to journalArticle

Liu, Feng Cheng ; Chang, Deh Ming ; Lai, Jenn Haung ; Lin, Chih Kung ; Chen, Hsiang Cheng ; Hou, Tsung Y. ; Kuo, San Yuan. / Autoimmune hepatitis with raised alpha-fetoprotein level as the presenting symptoms of systemic lupus erythematosus : A case report. In: Rheumatology International. 2007 ; Vol. 27, No. 5. pp. 489-491.
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