Associations between allergic diseases and attention deficit hyperactivity/oppositional defiant disorders in children

Yi Tsen Lin, Yang Ching Chen, Susan Shur Fen Gau, Te Huei Yeh, Hsien Yu Fan, Yu Ya Hwang, Yungling Leo Lee

Research output: Contribution to journalArticle

19 Citations (Scopus)


Background:We aim to investigate the detailed associations between allergic diseases with attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) among children.Methods:Clinical information from 2,896 children enrolled in the Taiwan Children Health Study was obtained for analyses. Allergic diseases, including atopic dermatitis, asthma, and allergic rhinitis, have been evaluated based on the questions adjusted from International Study of Asthma and Allergies in Childhood. The Swanson, Nolan, and Pelham questionnaire was used to assess symptoms of ADHD and ODD. Symptoms of depression, stress, and poor sleep quality were evaluated as the interactive risk factors.Results:Children having symptoms of allergic diseases within the past 1 y were associated with having all dimensions of symptoms of ADHD and ODD. Children with ever having a physician-diagnosed atopic dermatitis were associated with inattentive and hyperactive-impulsive symptoms of ADHD. Ever diagnosed asthma was associated with ADHD and ODD. Ever diagnosed allergic rhinitis was associated with inattentive and combined symptoms of ADHD and ODD.Conclusion:Children with allergic diseases, such as atopic dermatitis, asthma, and allergic rhinitis, were associated with exhibiting ADHD and ODD.

Original languageEnglish
Pages (from-to)480-485
Number of pages6
JournalPediatric Research
Issue number4
Publication statusPublished - Oct 1 2016


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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