Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

Y. T. Chang, H. S. Sun, C. S.J. Fann, C. J. Chang, Z. H. Liao, J. L. Huang, E. W. Loh, W. Y. Yu, A. T.A. Cheng

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In this study, five published single nucleotide polymorphisms in the GABAA receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).

Original languageEnglish
Pages (from-to)828-829
Number of pages2
JournalMolecular Psychiatry
Volume7
Issue number8
DOIs
Publication statusPublished - Jan 1 2002
Externally publishedYes

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Substance Withdrawal Syndrome
GABA Receptors
GABA-A Receptors
Multigene Family
Alcoholism
Single Nucleotide Polymorphism

ASJC Scopus subject areas

  • Molecular Biology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience

Cite this

Chang, Y. T., Sun, H. S., Fann, C. S. J., Chang, C. J., Liao, Z. H., Huang, J. L., ... Cheng, A. T. A. (2002). Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han. Molecular Psychiatry, 7(8), 828-829. https://doi.org/10.1038/sj.mp.4001110

Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han. / Chang, Y. T.; Sun, H. S.; Fann, C. S.J.; Chang, C. J.; Liao, Z. H.; Huang, J. L.; Loh, E. W.; Yu, W. Y.; Cheng, A. T.A.

In: Molecular Psychiatry, Vol. 7, No. 8, 01.01.2002, p. 828-829.

Research output: Contribution to journalArticle

Chang, YT, Sun, HS, Fann, CSJ, Chang, CJ, Liao, ZH, Huang, JL, Loh, EW, Yu, WY & Cheng, ATA 2002, 'Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han', Molecular Psychiatry, vol. 7, no. 8, pp. 828-829. https://doi.org/10.1038/sj.mp.4001110
Chang, Y. T. ; Sun, H. S. ; Fann, C. S.J. ; Chang, C. J. ; Liao, Z. H. ; Huang, J. L. ; Loh, E. W. ; Yu, W. Y. ; Cheng, A. T.A. / Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han. In: Molecular Psychiatry. 2002 ; Vol. 7, No. 8. pp. 828-829.
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