Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

Y. T. Chang; H. S. Sun; C. S.J. Fann; C. J. Chang; Z. H. Liao; J. L. Huang; E. W. Loh; W. Y. Yu; A. T.A. Cheng

doi:10.1038/sj.mp.4001110

Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

Y. T. Chang, H. S. Sun, C. S.J. Fann, C. J. Chang, Z. H. Liao, J. L. Huang, E. W. Loh, W. Y. Yu, A. T.A. Cheng

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

In this study, five published single nucleotide polymorphisms in the GABA_A receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).

Original language	English
Pages (from-to)	828-829
Number of pages	2
Journal	Molecular Psychiatry
Volume	7
Issue number	8
DOIs	https://doi.org/10.1038/sj.mp.4001110
Publication status	Published - 2002
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Psychiatry and Mental health
Cellular and Molecular Neuroscience

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.mp.4001110

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abstract = "In this study, five published single nucleotide polymorphisms in the GABAA receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).",

author = "Chang, {Y. T.} and Sun, {H. S.} and Fann, {C. S.J.} and Chang, {C. J.} and Liao, {Z. H.} and Huang, {J. L.} and Loh, {E. W.} and Yu, {W. Y.} and Cheng, {A. T.A.}",

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doi = "10.1038/sj.mp.4001110",

language = "English",

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AU - Chang, Y. T.

AU - Sun, H. S.

AU - Fann, C. S.J.

AU - Chang, C. J.

AU - Liao, Z. H.

AU - Huang, J. L.

AU - Loh, E. W.

AU - Yu, W. Y.

AU - Cheng, A. T.A.

PY - 2002

Y1 - 2002

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AB - In this study, five published single nucleotide polymorphisms in the GABAA receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).

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Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

Abstract

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