Abstract

Recent studies suggest that exposure to air pollution might be associated with severity of sleep-disordered breathing (SDB). However, the association between air pollution exposure, especially particulate matter with aerodynamic diameters <= 2.5 μm (PM2.5), and SDB is still unclear. We collected 4312 participants' data from the Taipei Medical University Hospital's Sleep Center and air pollution data from the Taiwan Environmental Protection Administration. Associations of particulate matter with aerodynamic diameters <=10 μm (PM10), PM2.5, nitrogen dioxide (NO2), ozone (O3) and sulfur dioxide (SO2) with apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were investigated by generalized additive models. We found that an interquartile range (IQR) increase in 1-year mean PM2.5 (3.4 μg/m3) and NO2 (2.7 ppb) was associated with a 4.7% and 3.6% increase in AHI, respectively. We also observed the association of an IQR increase in 1-year mean PM2.5 with a 2.5% increase in ODI. The similar pattern was found in the association of daily mean PM2.5 exposure with increased AHI. Moreover, participants showed significant AHI and ODI responses to air pollution levels in spring and winter. We concluded that exposure to PM2.5 was associated with SDB. Effects of air pollution on AHI and ODI were significant in spring and winter. PM2.5 was associated with sleep-disordered breathing among the general population in urban environments in spring and winter.

Original languageEnglish
Pages (from-to)109-113
Number of pages5
JournalEnvironmental Pollution
Volume233
DOIs
Publication statusPublished - Feb 1 2018

Fingerprint

Air Pollution
Sleep Apnea Syndromes
Apnea
Air pollution
Taiwan
Oxygen
Particulate Matter
Population
Aerodynamics
Nitrogen Dioxide
Sulfur Dioxide
Urban Population
Ozone
Conservation of Natural Resources
Sulfur dioxide
Environmental protection
Sleep
Nitrogen

Keywords

  • Air pollution
  • Apnea-hypopnea index
  • Oxygen desaturation index
  • PM
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

@article{ed7d4a90a1b7498086b2c977022c81d5,
title = "Association of PM2.5 with sleep-disordered breathing from a population-based study in Northern Taiwan urban areas",
abstract = "Recent studies suggest that exposure to air pollution might be associated with severity of sleep-disordered breathing (SDB). However, the association between air pollution exposure, especially particulate matter with aerodynamic diameters <= 2.5 μm (PM2.5), and SDB is still unclear. We collected 4312 participants' data from the Taipei Medical University Hospital's Sleep Center and air pollution data from the Taiwan Environmental Protection Administration. Associations of particulate matter with aerodynamic diameters <=10 μm (PM10), PM2.5, nitrogen dioxide (NO2), ozone (O3) and sulfur dioxide (SO2) with apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were investigated by generalized additive models. We found that an interquartile range (IQR) increase in 1-year mean PM2.5 (3.4 μg/m3) and NO2 (2.7 ppb) was associated with a 4.7{\%} and 3.6{\%} increase in AHI, respectively. We also observed the association of an IQR increase in 1-year mean PM2.5 with a 2.5{\%} increase in ODI. The similar pattern was found in the association of daily mean PM2.5 exposure with increased AHI. Moreover, participants showed significant AHI and ODI responses to air pollution levels in spring and winter. We concluded that exposure to PM2.5 was associated with SDB. Effects of air pollution on AHI and ODI were significant in spring and winter. PM2.5 was associated with sleep-disordered breathing among the general population in urban environments in spring and winter.",
keywords = "Air pollution, Apnea-hypopnea index, Oxygen desaturation index, PM, Sleep-disordered breathing",
author = "Shen, {Yen Ling} and Liu, {Wen Te} and Lee, {Kang Yun} and Chuang, {Hsiao Chi} and Chen, {Hua Wei} and Chuang, {Kai Jen}",
year = "2018",
month = "2",
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language = "English",
volume = "233",
pages = "109--113",
journal = "Environmental Pollution",
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TY - JOUR

T1 - Association of PM2.5 with sleep-disordered breathing from a population-based study in Northern Taiwan urban areas

AU - Shen, Yen Ling

AU - Liu, Wen Te

AU - Lee, Kang Yun

AU - Chuang, Hsiao Chi

AU - Chen, Hua Wei

AU - Chuang, Kai Jen

PY - 2018/2/1

Y1 - 2018/2/1

N2 - Recent studies suggest that exposure to air pollution might be associated with severity of sleep-disordered breathing (SDB). However, the association between air pollution exposure, especially particulate matter with aerodynamic diameters <= 2.5 μm (PM2.5), and SDB is still unclear. We collected 4312 participants' data from the Taipei Medical University Hospital's Sleep Center and air pollution data from the Taiwan Environmental Protection Administration. Associations of particulate matter with aerodynamic diameters <=10 μm (PM10), PM2.5, nitrogen dioxide (NO2), ozone (O3) and sulfur dioxide (SO2) with apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were investigated by generalized additive models. We found that an interquartile range (IQR) increase in 1-year mean PM2.5 (3.4 μg/m3) and NO2 (2.7 ppb) was associated with a 4.7% and 3.6% increase in AHI, respectively. We also observed the association of an IQR increase in 1-year mean PM2.5 with a 2.5% increase in ODI. The similar pattern was found in the association of daily mean PM2.5 exposure with increased AHI. Moreover, participants showed significant AHI and ODI responses to air pollution levels in spring and winter. We concluded that exposure to PM2.5 was associated with SDB. Effects of air pollution on AHI and ODI were significant in spring and winter. PM2.5 was associated with sleep-disordered breathing among the general population in urban environments in spring and winter.

AB - Recent studies suggest that exposure to air pollution might be associated with severity of sleep-disordered breathing (SDB). However, the association between air pollution exposure, especially particulate matter with aerodynamic diameters <= 2.5 μm (PM2.5), and SDB is still unclear. We collected 4312 participants' data from the Taipei Medical University Hospital's Sleep Center and air pollution data from the Taiwan Environmental Protection Administration. Associations of particulate matter with aerodynamic diameters <=10 μm (PM10), PM2.5, nitrogen dioxide (NO2), ozone (O3) and sulfur dioxide (SO2) with apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were investigated by generalized additive models. We found that an interquartile range (IQR) increase in 1-year mean PM2.5 (3.4 μg/m3) and NO2 (2.7 ppb) was associated with a 4.7% and 3.6% increase in AHI, respectively. We also observed the association of an IQR increase in 1-year mean PM2.5 with a 2.5% increase in ODI. The similar pattern was found in the association of daily mean PM2.5 exposure with increased AHI. Moreover, participants showed significant AHI and ODI responses to air pollution levels in spring and winter. We concluded that exposure to PM2.5 was associated with SDB. Effects of air pollution on AHI and ODI were significant in spring and winter. PM2.5 was associated with sleep-disordered breathing among the general population in urban environments in spring and winter.

KW - Air pollution

KW - Apnea-hypopnea index

KW - Oxygen desaturation index

KW - PM

KW - Sleep-disordered breathing

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U2 - 10.1016/j.envpol.2017.10.052

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JO - Environmental Pollution

JF - Environmental Pollution

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