Association of lifestyle factors with blood lipids and inflammation in adults aged 40 years and above: a population-based cross-sectional study in Taiwan

Miriam Adoyo Muga, Patrick Opiyo Owili, Chien Yeh Hsu, Jane C.J. Chao

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Lifestyle factors were associated with an increased risk of cardiovascular disease (CVD) occurrence. We explored the associations between lifestyle factors and CVD risk factors, and assessed the interactive effects of lifestyle factors on CVD risk factors. METHODS: A cross-sectional data of 114,082 (57,680 men and 56,402 women) middle-aged adults and elderly in Taiwan were collected from 2001 to 2010. Logistic regression analysis was used to assess the associations between lifestyle factors and CVD risk factors. The relative excess risk due to interaction (RERI) and the attributable proportion due to interaction were used to explore the interactive effect of lifestyle factors on CVD risk factors. RESULTS: The interaction between alcohol consumption and smoking exhibited an excess risk of high triglycerides (RERI = 0.21; 95% CI: 0.14-0.29), and that of alcohol consumption and physical activity had an excess risk of high LDL-cholesterol (RERI = 0.11; 95% CI: 0.06-0.16) and high blood glucose (RERI = 0.05; 95% CI: 0.01-0.11). Alcohol consumption and vegetable-rich diet (intake of high vegetables with no or low meat) had an excess risk of high LDL-cholesterol and low HDL-cholesterol, but a reduced risk of high triglycerides (RERI = - 0.10; 95% CI: - 0.17 - -0.04). Smoking and physical activity had an increased risk of high blood glucose and a reduced risk of low HDL-cholesterol. Smoking and vegetable-rich diet reduced the risk of high triglycerides (RERI = - 0.11; 95% CI: - 0.18 - - 0.04), high blood glucose (RERI = - 0.14; 95% CI: - 0.21 - - 0.07) and low HDL-cholesterol (RERI = - 0.10; 95% CI: - 0.19 - -0.01). CONCLUSIONS: The interaction between smoking, alcohol consumption, physical activity and diet were associated with lipid profile and blood glucose, hence there was an interaction between these lifestyle factors in an additive scale. Public health promotion should therefore consider multifaceted promotional activities that are likely to make a positive impact on the health status of the Taiwanese population.

Original languageEnglish
Number of pages1
JournalBMC Public Health
Volume19
Issue number1
DOIs
Publication statusPublished - Oct 22 2019

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Taiwan
Life Style
Cross-Sectional Studies
Inflammation
Lipids
Population
Cardiovascular Diseases
Alcohol Drinking
Blood Glucose
Smoking
Vegetables
HDL Cholesterol
Triglycerides
Exercise
Diet
LDL Cholesterol
Health Promotion
Meat
Health Status

Keywords

  • Blood lipids
  • Cardiovascular disease
  • Inflammation
  • Lifestyle factors

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Association of lifestyle factors with blood lipids and inflammation in adults aged 40 years and above : a population-based cross-sectional study in Taiwan. / Muga, Miriam Adoyo; Owili, Patrick Opiyo; Hsu, Chien Yeh; Chao, Jane C.J.

In: BMC Public Health, Vol. 19, No. 1, 22.10.2019.

Research output: Contribution to journalArticle

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abstract = "BACKGROUND: Lifestyle factors were associated with an increased risk of cardiovascular disease (CVD) occurrence. We explored the associations between lifestyle factors and CVD risk factors, and assessed the interactive effects of lifestyle factors on CVD risk factors. METHODS: A cross-sectional data of 114,082 (57,680 men and 56,402 women) middle-aged adults and elderly in Taiwan were collected from 2001 to 2010. Logistic regression analysis was used to assess the associations between lifestyle factors and CVD risk factors. The relative excess risk due to interaction (RERI) and the attributable proportion due to interaction were used to explore the interactive effect of lifestyle factors on CVD risk factors. RESULTS: The interaction between alcohol consumption and smoking exhibited an excess risk of high triglycerides (RERI = 0.21; 95{\%} CI: 0.14-0.29), and that of alcohol consumption and physical activity had an excess risk of high LDL-cholesterol (RERI = 0.11; 95{\%} CI: 0.06-0.16) and high blood glucose (RERI = 0.05; 95{\%} CI: 0.01-0.11). Alcohol consumption and vegetable-rich diet (intake of high vegetables with no or low meat) had an excess risk of high LDL-cholesterol and low HDL-cholesterol, but a reduced risk of high triglycerides (RERI = - 0.10; 95{\%} CI: - 0.17 - -0.04). Smoking and physical activity had an increased risk of high blood glucose and a reduced risk of low HDL-cholesterol. Smoking and vegetable-rich diet reduced the risk of high triglycerides (RERI = - 0.11; 95{\%} CI: - 0.18 - - 0.04), high blood glucose (RERI = - 0.14; 95{\%} CI: - 0.21 - - 0.07) and low HDL-cholesterol (RERI = - 0.10; 95{\%} CI: - 0.19 - -0.01). CONCLUSIONS: The interaction between smoking, alcohol consumption, physical activity and diet were associated with lipid profile and blood glucose, hence there was an interaction between these lifestyle factors in an additive scale. Public health promotion should therefore consider multifaceted promotional activities that are likely to make a positive impact on the health status of the Taiwanese population.",
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T1 - Association of lifestyle factors with blood lipids and inflammation in adults aged 40 years and above

T2 - a population-based cross-sectional study in Taiwan

AU - Muga, Miriam Adoyo

AU - Owili, Patrick Opiyo

AU - Hsu, Chien Yeh

AU - Chao, Jane C.J.

PY - 2019/10/22

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N2 - BACKGROUND: Lifestyle factors were associated with an increased risk of cardiovascular disease (CVD) occurrence. We explored the associations between lifestyle factors and CVD risk factors, and assessed the interactive effects of lifestyle factors on CVD risk factors. METHODS: A cross-sectional data of 114,082 (57,680 men and 56,402 women) middle-aged adults and elderly in Taiwan were collected from 2001 to 2010. Logistic regression analysis was used to assess the associations between lifestyle factors and CVD risk factors. The relative excess risk due to interaction (RERI) and the attributable proportion due to interaction were used to explore the interactive effect of lifestyle factors on CVD risk factors. RESULTS: The interaction between alcohol consumption and smoking exhibited an excess risk of high triglycerides (RERI = 0.21; 95% CI: 0.14-0.29), and that of alcohol consumption and physical activity had an excess risk of high LDL-cholesterol (RERI = 0.11; 95% CI: 0.06-0.16) and high blood glucose (RERI = 0.05; 95% CI: 0.01-0.11). Alcohol consumption and vegetable-rich diet (intake of high vegetables with no or low meat) had an excess risk of high LDL-cholesterol and low HDL-cholesterol, but a reduced risk of high triglycerides (RERI = - 0.10; 95% CI: - 0.17 - -0.04). Smoking and physical activity had an increased risk of high blood glucose and a reduced risk of low HDL-cholesterol. Smoking and vegetable-rich diet reduced the risk of high triglycerides (RERI = - 0.11; 95% CI: - 0.18 - - 0.04), high blood glucose (RERI = - 0.14; 95% CI: - 0.21 - - 0.07) and low HDL-cholesterol (RERI = - 0.10; 95% CI: - 0.19 - -0.01). CONCLUSIONS: The interaction between smoking, alcohol consumption, physical activity and diet were associated with lipid profile and blood glucose, hence there was an interaction between these lifestyle factors in an additive scale. Public health promotion should therefore consider multifaceted promotional activities that are likely to make a positive impact on the health status of the Taiwanese population.

AB - BACKGROUND: Lifestyle factors were associated with an increased risk of cardiovascular disease (CVD) occurrence. We explored the associations between lifestyle factors and CVD risk factors, and assessed the interactive effects of lifestyle factors on CVD risk factors. METHODS: A cross-sectional data of 114,082 (57,680 men and 56,402 women) middle-aged adults and elderly in Taiwan were collected from 2001 to 2010. Logistic regression analysis was used to assess the associations between lifestyle factors and CVD risk factors. The relative excess risk due to interaction (RERI) and the attributable proportion due to interaction were used to explore the interactive effect of lifestyle factors on CVD risk factors. RESULTS: The interaction between alcohol consumption and smoking exhibited an excess risk of high triglycerides (RERI = 0.21; 95% CI: 0.14-0.29), and that of alcohol consumption and physical activity had an excess risk of high LDL-cholesterol (RERI = 0.11; 95% CI: 0.06-0.16) and high blood glucose (RERI = 0.05; 95% CI: 0.01-0.11). Alcohol consumption and vegetable-rich diet (intake of high vegetables with no or low meat) had an excess risk of high LDL-cholesterol and low HDL-cholesterol, but a reduced risk of high triglycerides (RERI = - 0.10; 95% CI: - 0.17 - -0.04). Smoking and physical activity had an increased risk of high blood glucose and a reduced risk of low HDL-cholesterol. Smoking and vegetable-rich diet reduced the risk of high triglycerides (RERI = - 0.11; 95% CI: - 0.18 - - 0.04), high blood glucose (RERI = - 0.14; 95% CI: - 0.21 - - 0.07) and low HDL-cholesterol (RERI = - 0.10; 95% CI: - 0.19 - -0.01). CONCLUSIONS: The interaction between smoking, alcohol consumption, physical activity and diet were associated with lipid profile and blood glucose, hence there was an interaction between these lifestyle factors in an additive scale. Public health promotion should therefore consider multifaceted promotional activities that are likely to make a positive impact on the health status of the Taiwanese population.

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KW - Inflammation

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