Association of attention-deficit/hyperactivity disorder with diabetes: A population-based study

Hui Ju Chen, Yann Jinn Lee, Geng Chang Yeh, Herng Ching Lin

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Background:Cognitive impairment has been documented in adult diabetes but is unclear in pediatric diabetes. No study had been conducted to explore the relationship between attention-deficit/hyperactivity disorder (ADHD) and diabetes. Using a population-based data set, we aimed to examine the association between ADHD and a prior diagnosis of diabetes mellitus (DM) in Taiwan.Methods:A total of 4,302 patients with ADHD were selected as cases and 21,510 randomly selected subjects as controls. We used conditional logistic regression to calculate the odds ratio (OR) for having previously received a diagnosis of DM between subjects with and without ADHD.Results:In this study, 116 of the 25,812 sampled subjects (0.5%) had received a diagnosis of DM prior to their index date. Subjects with ADHD had a higher proportion of prior DM diagnoses than controls (0.9% vs. 0.4%, P <0.001). After adjusting for age, sex, index year, geographic location, and obesity, ADHD was significantly associated with a prior diagnosis of type 2 DM (OR = 2.75, 95% confidence interval (CI) = 1.82-4.16). However, no significant association was observed between ADHD and type 1 DM.Conclusion:The findings suggest that ADHD was associated with a previous diagnosis of type 2 DM.

Original languageEnglish
Pages (from-to)492-496
Number of pages5
JournalPediatric Research
Volume73
Issue number4
DOIs
Publication statusPublished - Apr 2013

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Attention Deficit Disorder with Hyperactivity
Population
Diabetes Mellitus
Type 2 Diabetes Mellitus
Odds Ratio
Geographic Locations
Type 1 Diabetes Mellitus
Taiwan
Obesity
Logistic Models
Confidence Intervals
Pediatrics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Association of attention-deficit/hyperactivity disorder with diabetes : A population-based study. / Chen, Hui Ju; Lee, Yann Jinn; Yeh, Geng Chang; Lin, Herng Ching.

In: Pediatric Research, Vol. 73, No. 4, 04.2013, p. 492-496.

Research output: Contribution to journalArticle

Chen, Hui Ju ; Lee, Yann Jinn ; Yeh, Geng Chang ; Lin, Herng Ching. / Association of attention-deficit/hyperactivity disorder with diabetes : A population-based study. In: Pediatric Research. 2013 ; Vol. 73, No. 4. pp. 492-496.
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