Association of Anti-Ro/Sjögren’s syndrome type A antibodies and complete atrioventricular block in an adult with Sjögren’s syndrome

Weng Kin Tam, Hui Ching Hsu, Ming Hsiung Hsieh, Jong Shiuan Yeh, Weng Chio Tam

Research output: Contribution to journalArticle

Abstract

A 57-year-old female patient with underlying hypertension, dyslipidemia, membranous glomerulonephritis, and Sjögren’s syndrome (SS) presented to our clinic with near-syncope and dizziness symptoms. We detected non-conducted sinus beat in 12-lead electrocardiography. An echocardiography showed that the left ventricular systolic function was preserved without a regional wall abnormality. The patient did not have symptoms of congestive heart failure or recent myocardial infarction. We observed complete atrioventricular block (CAVB) with longest pause of 6.2 seconds in a 24-hour Holter electrocardiography, and subsequently implanted a permanent pacemaker. Anti-Ro/SS type A antibodies are commonly seen in SS and associated with a neonatal complete heart block. The pathogenesis of anti-Ro/SS type A antibodies in the conduction system of an adult heart is still uncertain. In this article, we report SS in an adult patient with CAVB and membranous glomerulonephritis, which may be associated with a positive titer of anti-Ro/SS type A antibodies.

Original languageEnglish
Pages (from-to)225-229
Number of pages5
JournalArchives of Rheumatology
Volume33
Issue number2
DOIs
Publication statusPublished - Jun 1 2018

Fingerprint

Atrioventricular Block
Antibodies
Membranous Glomerulonephritis
Heart Conduction System
Ambulatory Electrocardiography
Heart Block
Syncope
Dizziness
Dyslipidemias
Left Ventricular Function
Echocardiography
Electrocardiography
Heart Failure
Myocardial Infarction
Hypertension

Keywords

  • Anti-Ro/Sjögren’s syndrome type A antibodies
  • Complete atrioventricular block
  • Sjögren’s syndrome

ASJC Scopus subject areas

  • Rheumatology

Cite this

Association of Anti-Ro/Sjögren’s syndrome type A antibodies and complete atrioventricular block in an adult with Sjögren’s syndrome. / Tam, Weng Kin; Hsu, Hui Ching; Hsieh, Ming Hsiung; Yeh, Jong Shiuan; Tam, Weng Chio.

In: Archives of Rheumatology, Vol. 33, No. 2, 01.06.2018, p. 225-229.

Research output: Contribution to journalArticle

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