Association between stroke and patients with pelvic inflammatory disease: A nationwide population-based study in taiwan

Po Chih Chen, Teng Chu Tseng, Jui Yang Hsieh, Hui Wen Lin

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background and Purpose- The aim of this study is to estimate the risk of stroke in a 3-year period after pelvic inflammatory disease (PID) using a nationwide population-based study. Methods- Our study cohort consisted of all patients with a diagnosis of PID (N=64 515) between 2004 and 2005 with a control cohort (1:2) of age-matched controls (N=129 030). Each patient was tracked from hospitalization until the end of 2006. Cox regressions were performed to compute the 3-year stroke-free survival rates after adjusting for possible confounding factors. Results- We found that women with PID were more likely to have strokes than the control population. After adjusting for potential confounding factors, the adjusted hazard ratio of stroke was 1.63 (95% CI, 1.45-1.85) for PID patients as compared to the general population cohort. Sensitivity analysis using a bootstrap approach further ensured the validity of the results of our study. Conclusions- We concluded that patients with PID have an association with stroke. Further research is necessary to investigate the pathophysiology between PID and stroke.

Original languageEnglish
Pages (from-to)2074-2076
Number of pages3
JournalStroke
Volume42
Issue number7
DOIs
Publication statusPublished - Jul 1 2011

Keywords

  • epidemiology
  • pelvic inflammatory disease
  • risk factors
  • sensitivity analysis
  • stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialised Nursing

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