Association between platelet count and components of metabolic syndrome in geriatric taiwanese males

Yen Ling Chang, Chun Pei, Dee Pei, Sai Hung Tang, Chun Hsien Hsu, Yen Lin Chen, Te Lin Hsia, Jiunn Diann Lin, Chung Ze Wu, Jin Biou Chang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: With the growing number of elderly population in Taiwan and many other countries, the role of metabolic syndrome (MetS) has become more important recently. Although had been reported in different age groups, the relationship between platelet and MetS in the geriatric population still remains unknown. Methods: We included 1187 Taiwanese males who were older than 65 years. In this study, we excluded individuals with abnormal platelet counts to reveal a more clear relation between platelet counts and MetS. Platelet counts were analyzed among patients with and without MetS. We divided platelet counts into four groups according to quartiles arbitrary of platelet counts (lowest, PC1; highest, PC4). The number of MetS components was compared between platelet groups with analysis of variance. We also used simple correlation and multivariate linear regression to find the relationship between platelet counts and MetS components. Results: We found that the platelet counts were higher in the group with MetS but not significantly different (p = 0.675). The fasting plasma glucose (FPG), total cholesterol, low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG), and Log-triglyceride (Log-TG) were all statistically different across the four platelet groups. These four components were also positively correlated to platelet count in simple correlation. Not surprisingly, FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count in multivariate linear regression. Conclusion: FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count among the MetS components in geriatric Taiwanese males. The role of HDL-C and LDL-C in the definition of MetS should be re-evaluated.

Original languageEnglish
Pages (from-to)215-219
Number of pages5
JournalInternational Journal of Gerontology
Volume6
Issue number3
DOIs
Publication statusPublished - Sep 2012

Fingerprint

Platelet Count
Geriatrics
LDL Cholesterol
Fasting
Triglycerides
Blood Platelets
Glucose
Linear Models
Taiwan
Population
Analysis of Variance
Age Groups
Cholesterol

Keywords

  • body mass index
  • low-density lipoprotein-cholesterol
  • metabolic syndrome
  • platelet count
  • triglyceride

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Association between platelet count and components of metabolic syndrome in geriatric taiwanese males. / Chang, Yen Ling; Pei, Chun; Pei, Dee; Tang, Sai Hung; Hsu, Chun Hsien; Chen, Yen Lin; Hsia, Te Lin; Lin, Jiunn Diann; Wu, Chung Ze; Chang, Jin Biou.

In: International Journal of Gerontology, Vol. 6, No. 3, 09.2012, p. 215-219.

Research output: Contribution to journalArticle

Chang, Yen Ling ; Pei, Chun ; Pei, Dee ; Tang, Sai Hung ; Hsu, Chun Hsien ; Chen, Yen Lin ; Hsia, Te Lin ; Lin, Jiunn Diann ; Wu, Chung Ze ; Chang, Jin Biou. / Association between platelet count and components of metabolic syndrome in geriatric taiwanese males. In: International Journal of Gerontology. 2012 ; Vol. 6, No. 3. pp. 215-219.
@article{837ce7aa7feb44c09740866d7d1cfcfe,
title = "Association between platelet count and components of metabolic syndrome in geriatric taiwanese males",
abstract = "Background: With the growing number of elderly population in Taiwan and many other countries, the role of metabolic syndrome (MetS) has become more important recently. Although had been reported in different age groups, the relationship between platelet and MetS in the geriatric population still remains unknown. Methods: We included 1187 Taiwanese males who were older than 65 years. In this study, we excluded individuals with abnormal platelet counts to reveal a more clear relation between platelet counts and MetS. Platelet counts were analyzed among patients with and without MetS. We divided platelet counts into four groups according to quartiles arbitrary of platelet counts (lowest, PC1; highest, PC4). The number of MetS components was compared between platelet groups with analysis of variance. We also used simple correlation and multivariate linear regression to find the relationship between platelet counts and MetS components. Results: We found that the platelet counts were higher in the group with MetS but not significantly different (p = 0.675). The fasting plasma glucose (FPG), total cholesterol, low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG), and Log-triglyceride (Log-TG) were all statistically different across the four platelet groups. These four components were also positively correlated to platelet count in simple correlation. Not surprisingly, FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count in multivariate linear regression. Conclusion: FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count among the MetS components in geriatric Taiwanese males. The role of HDL-C and LDL-C in the definition of MetS should be re-evaluated.",
keywords = "body mass index, low-density lipoprotein-cholesterol, metabolic syndrome, platelet count, triglyceride",
author = "Chang, {Yen Ling} and Chun Pei and Dee Pei and Tang, {Sai Hung} and Hsu, {Chun Hsien} and Chen, {Yen Lin} and Hsia, {Te Lin} and Lin, {Jiunn Diann} and Wu, {Chung Ze} and Chang, {Jin Biou}",
year = "2012",
month = "9",
doi = "10.1016/j.ijge.2012.01.021",
language = "English",
volume = "6",
pages = "215--219",
journal = "International Journal of Gerontology",
issn = "1873-9598",
publisher = "Elsevier Taiwan LLC",
number = "3",

}

TY - JOUR

T1 - Association between platelet count and components of metabolic syndrome in geriatric taiwanese males

AU - Chang, Yen Ling

AU - Pei, Chun

AU - Pei, Dee

AU - Tang, Sai Hung

AU - Hsu, Chun Hsien

AU - Chen, Yen Lin

AU - Hsia, Te Lin

AU - Lin, Jiunn Diann

AU - Wu, Chung Ze

AU - Chang, Jin Biou

PY - 2012/9

Y1 - 2012/9

N2 - Background: With the growing number of elderly population in Taiwan and many other countries, the role of metabolic syndrome (MetS) has become more important recently. Although had been reported in different age groups, the relationship between platelet and MetS in the geriatric population still remains unknown. Methods: We included 1187 Taiwanese males who were older than 65 years. In this study, we excluded individuals with abnormal platelet counts to reveal a more clear relation between platelet counts and MetS. Platelet counts were analyzed among patients with and without MetS. We divided platelet counts into four groups according to quartiles arbitrary of platelet counts (lowest, PC1; highest, PC4). The number of MetS components was compared between platelet groups with analysis of variance. We also used simple correlation and multivariate linear regression to find the relationship between platelet counts and MetS components. Results: We found that the platelet counts were higher in the group with MetS but not significantly different (p = 0.675). The fasting plasma glucose (FPG), total cholesterol, low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG), and Log-triglyceride (Log-TG) were all statistically different across the four platelet groups. These four components were also positively correlated to platelet count in simple correlation. Not surprisingly, FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count in multivariate linear regression. Conclusion: FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count among the MetS components in geriatric Taiwanese males. The role of HDL-C and LDL-C in the definition of MetS should be re-evaluated.

AB - Background: With the growing number of elderly population in Taiwan and many other countries, the role of metabolic syndrome (MetS) has become more important recently. Although had been reported in different age groups, the relationship between platelet and MetS in the geriatric population still remains unknown. Methods: We included 1187 Taiwanese males who were older than 65 years. In this study, we excluded individuals with abnormal platelet counts to reveal a more clear relation between platelet counts and MetS. Platelet counts were analyzed among patients with and without MetS. We divided platelet counts into four groups according to quartiles arbitrary of platelet counts (lowest, PC1; highest, PC4). The number of MetS components was compared between platelet groups with analysis of variance. We also used simple correlation and multivariate linear regression to find the relationship between platelet counts and MetS components. Results: We found that the platelet counts were higher in the group with MetS but not significantly different (p = 0.675). The fasting plasma glucose (FPG), total cholesterol, low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG), and Log-triglyceride (Log-TG) were all statistically different across the four platelet groups. These four components were also positively correlated to platelet count in simple correlation. Not surprisingly, FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count in multivariate linear regression. Conclusion: FPG, LDL-C, TG, and Log-TG were positively correlated with platelet count among the MetS components in geriatric Taiwanese males. The role of HDL-C and LDL-C in the definition of MetS should be re-evaluated.

KW - body mass index

KW - low-density lipoprotein-cholesterol

KW - metabolic syndrome

KW - platelet count

KW - triglyceride

UR - http://www.scopus.com/inward/record.url?scp=84866730179&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866730179&partnerID=8YFLogxK

U2 - 10.1016/j.ijge.2012.01.021

DO - 10.1016/j.ijge.2012.01.021

M3 - Article

AN - SCOPUS:84866730179

VL - 6

SP - 215

EP - 219

JO - International Journal of Gerontology

JF - International Journal of Gerontology

SN - 1873-9598

IS - 3

ER -