Abstract

Using a nationwide population-based dataset, the aim of the present study was to investigate the association between paternal schizophrenia and the risk of low birthweight (LBW). This study linked the 2001 Taiwan National Health Insurance Research Dataset with Taiwan's birth and death certificate registries. In total, 220465 singleton live births were included. The key dependent variable was whether or not an infant's father was diagnosed with schizophrenia, while the independent variable of interest was whether an infant had LBW. Multivariate logistic regression analysis was performed to explore the relationship between paternal schizophrenia and the risk of LBW, after adjusting for the infant and parents' characteristics. The results show that infants whose fathers had schizophrenia were more likely to have LBW than those whose fathers did not (12.6% vs 8.0%). Infants whose fathers had schizophrenia were found to be 1.58 (95% confidence interval=1.10-2.52, P

Original languageEnglish
Pages (from-to)624-630
Number of pages7
JournalSchizophrenia Bulletin
Volume35
Issue number3
DOIs
Publication statusPublished - May 2009

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Schizophrenia
Fathers
Population
Taiwan
Birth Certificates
Death Certificates
National Health Programs
Live Birth
Registries
Parents
Logistic Models
Regression Analysis
Confidence Intervals
Research
Datasets

Keywords

  • Birthweight
  • Paternal schizophrenia
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

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title = "Association between paternal Schizophrenia and low birthweight: A nationwide population-based study",
abstract = "Using a nationwide population-based dataset, the aim of the present study was to investigate the association between paternal schizophrenia and the risk of low birthweight (LBW). This study linked the 2001 Taiwan National Health Insurance Research Dataset with Taiwan's birth and death certificate registries. In total, 220465 singleton live births were included. The key dependent variable was whether or not an infant's father was diagnosed with schizophrenia, while the independent variable of interest was whether an infant had LBW. Multivariate logistic regression analysis was performed to explore the relationship between paternal schizophrenia and the risk of LBW, after adjusting for the infant and parents' characteristics. The results show that infants whose fathers had schizophrenia were more likely to have LBW than those whose fathers did not (12.6{\%} vs 8.0{\%}). Infants whose fathers had schizophrenia were found to be 1.58 (95{\%} confidence interval=1.10-2.52, P",
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AU - Lin, Herng Ching

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AU - Lee, Hsin Chien

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AB - Using a nationwide population-based dataset, the aim of the present study was to investigate the association between paternal schizophrenia and the risk of low birthweight (LBW). This study linked the 2001 Taiwan National Health Insurance Research Dataset with Taiwan's birth and death certificate registries. In total, 220465 singleton live births were included. The key dependent variable was whether or not an infant's father was diagnosed with schizophrenia, while the independent variable of interest was whether an infant had LBW. Multivariate logistic regression analysis was performed to explore the relationship between paternal schizophrenia and the risk of LBW, after adjusting for the infant and parents' characteristics. The results show that infants whose fathers had schizophrenia were more likely to have LBW than those whose fathers did not (12.6% vs 8.0%). Infants whose fathers had schizophrenia were found to be 1.58 (95% confidence interval=1.10-2.52, P

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