Association between multiple sclerosis and chronic periodontitis: A population-based pilot study

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Background and purpose: The pathogenesis of multiple sclerosis (MS) is still not fully understood, but multiple infections are known to be crucial in the development of the disease. Periodontitis caused by periodontopathic polymicrobial infections is among the most common chronic infectious disorders. This case-control study aimed to investigate the association between chronic periodontitis (CP) and MS using a population-based dataset in Taiwan. Methods: This study included 316 cases who had a diagnosis of MS and 1580 randomly selected controls. We performed conditional logistic regressions to investigate the association between MS and having been previously diagnosed with CP. Results: The results reveal that the prevalence of earlier CP was 25.6% and 15.4% for cases and controls, respectively (P

Original languageEnglish
Pages (from-to)1053-1059
Number of pages7
JournalEuropean Journal of Neurology
Volume20
Issue number7
DOIs
Publication statusPublished - Jul 2013

Fingerprint

Chronic Periodontitis
Multiple Sclerosis
Population
Periodontitis
Coinfection
Taiwan
Case-Control Studies
Logistic Models
Infection

Keywords

  • Chronic periodontitis
  • Multiple sclerosis
  • Periodontitis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Association between multiple sclerosis and chronic periodontitis : A population-based pilot study. / Sheu, J. J.; Lin, H. C.

In: European Journal of Neurology, Vol. 20, No. 7, 07.2013, p. 1053-1059.

Research output: Contribution to journalArticle

@article{23fe63bb6d054a9c968865effe0d4feb,
title = "Association between multiple sclerosis and chronic periodontitis: A population-based pilot study",
abstract = "Background and purpose: The pathogenesis of multiple sclerosis (MS) is still not fully understood, but multiple infections are known to be crucial in the development of the disease. Periodontitis caused by periodontopathic polymicrobial infections is among the most common chronic infectious disorders. This case-control study aimed to investigate the association between chronic periodontitis (CP) and MS using a population-based dataset in Taiwan. Methods: This study included 316 cases who had a diagnosis of MS and 1580 randomly selected controls. We performed conditional logistic regressions to investigate the association between MS and having been previously diagnosed with CP. Results: The results reveal that the prevalence of earlier CP was 25.6{\%} and 15.4{\%} for cases and controls, respectively (P",
keywords = "Chronic periodontitis, Multiple sclerosis, Periodontitis",
author = "Sheu, {J. J.} and Lin, {H. C.}",
year = "2013",
month = "7",
doi = "10.1111/ene.12103",
language = "English",
volume = "20",
pages = "1053--1059",
journal = "European Journal of Neurology",
issn = "1351-5101",
publisher = "Wiley-Blackwell",
number = "7",

}

TY - JOUR

T1 - Association between multiple sclerosis and chronic periodontitis

T2 - A population-based pilot study

AU - Sheu, J. J.

AU - Lin, H. C.

PY - 2013/7

Y1 - 2013/7

N2 - Background and purpose: The pathogenesis of multiple sclerosis (MS) is still not fully understood, but multiple infections are known to be crucial in the development of the disease. Periodontitis caused by periodontopathic polymicrobial infections is among the most common chronic infectious disorders. This case-control study aimed to investigate the association between chronic periodontitis (CP) and MS using a population-based dataset in Taiwan. Methods: This study included 316 cases who had a diagnosis of MS and 1580 randomly selected controls. We performed conditional logistic regressions to investigate the association between MS and having been previously diagnosed with CP. Results: The results reveal that the prevalence of earlier CP was 25.6% and 15.4% for cases and controls, respectively (P

AB - Background and purpose: The pathogenesis of multiple sclerosis (MS) is still not fully understood, but multiple infections are known to be crucial in the development of the disease. Periodontitis caused by periodontopathic polymicrobial infections is among the most common chronic infectious disorders. This case-control study aimed to investigate the association between chronic periodontitis (CP) and MS using a population-based dataset in Taiwan. Methods: This study included 316 cases who had a diagnosis of MS and 1580 randomly selected controls. We performed conditional logistic regressions to investigate the association between MS and having been previously diagnosed with CP. Results: The results reveal that the prevalence of earlier CP was 25.6% and 15.4% for cases and controls, respectively (P

KW - Chronic periodontitis

KW - Multiple sclerosis

KW - Periodontitis

UR - http://www.scopus.com/inward/record.url?scp=84879005633&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879005633&partnerID=8YFLogxK

U2 - 10.1111/ene.12103

DO - 10.1111/ene.12103

M3 - Article

C2 - 23398363

AN - SCOPUS:84879005633

VL - 20

SP - 1053

EP - 1059

JO - European Journal of Neurology

JF - European Journal of Neurology

SN - 1351-5101

IS - 7

ER -