Association between emphysema score, six-minute walk and cardiopulmonary exercise tests in COPD

Li Fei Chen; Chun Hua Wang; Pai Chien Chou; Shu Chuan Ho; Wen Ching Joa; Te Fang Sheng; Han Pin Kuo

doi:10.2174/1874306401206010104

Association between emphysema score, six-minute walk and cardiopulmonary exercise tests in COPD

Li Fei Chen, Chun Hua Wang, Pai Chien Chou, Shu Chuan Ho, Wen Ching Joa, Te Fang Sheng, Han Pin Kuo

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Background: High-resolution computed tomography (HRCT) has allowed in detection of airway wall abnormalities and emphysema, whose extent may correlate with the clinical severity of the disease in patients with chronic obstructive pulmonary disease (COPD). Six minute walk test (6MWT) and cardiopulmonary exercise test (CPET) can determine functional status. Methods: A study was undertaken to investigate whether the extent of emphysema in COPD patients quantitatively confirmed by HRCT scoring was associated with distance walked, inspiratory capacity (IC) changes after exercise, anaerobic threshold of cardiopulmonary exercise and the BODE index (body mass index, airflow obstruction, dyspnea, exercise performance). Results: Seventeen patients with COPD underwent HRCT scanning, 6MWT and CPET. The emphysema score was highly correlated to forced vital capacity (FVC) (r=-0.748, p2 max (r=-0.514, p

Original language	English
Pages (from-to)	104-110
Number of pages	7
Journal	Open Respiratory Medicine Journal
Volume	6
Issue number	1
DOIs	https://doi.org/10.2174/1874306401206010104
Publication status	Published - 2012
Externally published	Yes

Keywords

Cardiopulmonary exercise test
Chronic obstructive pulmonary disease
High-resolution computed tomography
Inspiratory capacity
Six-minute walk test

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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Cite this

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title = "Association between emphysema score, six-minute walk and cardiopulmonary exercise tests in COPD",

abstract = "Background: High-resolution computed tomography (HRCT) has allowed in detection of airway wall abnormalities and emphysema, whose extent may correlate with the clinical severity of the disease in patients with chronic obstructive pulmonary disease (COPD). Six minute walk test (6MWT) and cardiopulmonary exercise test (CPET) can determine functional status. Methods: A study was undertaken to investigate whether the extent of emphysema in COPD patients quantitatively confirmed by HRCT scoring was associated with distance walked, inspiratory capacity (IC) changes after exercise, anaerobic threshold of cardiopulmonary exercise and the BODE index (body mass index, airflow obstruction, dyspnea, exercise performance). Results: Seventeen patients with COPD underwent HRCT scanning, 6MWT and CPET. The emphysema score was highly correlated to forced vital capacity (FVC) (r=-0.748, p2 max (r=-0.514, p",

keywords = "Cardiopulmonary exercise test, Chronic obstructive pulmonary disease, High-resolution computed tomography, Inspiratory capacity, Six-minute walk test",

author = "Chen, {Li Fei} and Wang, {Chun Hua} and Chou, {Pai Chien} and Ho, {Shu Chuan} and Joa, {Wen Ching} and Sheng, {Te Fang} and Kuo, {Han Pin}",

year = "2012",

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language = "English",

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T1 - Association between emphysema score, six-minute walk and cardiopulmonary exercise tests in COPD

AU - Chen, Li Fei

AU - Wang, Chun Hua

AU - Chou, Pai Chien

AU - Ho, Shu Chuan

AU - Joa, Wen Ching

AU - Sheng, Te Fang

AU - Kuo, Han Pin

PY - 2012

Y1 - 2012

N2 - Background: High-resolution computed tomography (HRCT) has allowed in detection of airway wall abnormalities and emphysema, whose extent may correlate with the clinical severity of the disease in patients with chronic obstructive pulmonary disease (COPD). Six minute walk test (6MWT) and cardiopulmonary exercise test (CPET) can determine functional status. Methods: A study was undertaken to investigate whether the extent of emphysema in COPD patients quantitatively confirmed by HRCT scoring was associated with distance walked, inspiratory capacity (IC) changes after exercise, anaerobic threshold of cardiopulmonary exercise and the BODE index (body mass index, airflow obstruction, dyspnea, exercise performance). Results: Seventeen patients with COPD underwent HRCT scanning, 6MWT and CPET. The emphysema score was highly correlated to forced vital capacity (FVC) (r=-0.748, p2 max (r=-0.514, p

AB - Background: High-resolution computed tomography (HRCT) has allowed in detection of airway wall abnormalities and emphysema, whose extent may correlate with the clinical severity of the disease in patients with chronic obstructive pulmonary disease (COPD). Six minute walk test (6MWT) and cardiopulmonary exercise test (CPET) can determine functional status. Methods: A study was undertaken to investigate whether the extent of emphysema in COPD patients quantitatively confirmed by HRCT scoring was associated with distance walked, inspiratory capacity (IC) changes after exercise, anaerobic threshold of cardiopulmonary exercise and the BODE index (body mass index, airflow obstruction, dyspnea, exercise performance). Results: Seventeen patients with COPD underwent HRCT scanning, 6MWT and CPET. The emphysema score was highly correlated to forced vital capacity (FVC) (r=-0.748, p2 max (r=-0.514, p

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KW - Chronic obstructive pulmonary disease

KW - High-resolution computed tomography

KW - Inspiratory capacity

KW - Six-minute walk test

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