Association between allergic rhinitis and nasopharyngeal carcinoma: A population-based study

Shiu Dong Chung, Chuan Song Wu, Herng Ching Lin, Shih Han Hung

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objectives/Hypothesis Although it is known that inflammatory processes can elevate the risk of cancer, to date the association between allergic rhinitis (AR) and nasopharyngeal carcinoma (NPC) remains unknown. This study aimed to evaluate the association between NPC and AR based on a population-based database in Taiwan. Study Design A case-control study. Methods In total, 1,799 NPC cases and 5,397 randomly selected controls without NPC were included. We evaluated the prevalence and risk of prior AR between cases and controls. We also performed a conditional logistic regression analysis to calculate the odds ratio (OR) for having been previously diagnosed with AR between cases and controls. Results In total, 2,453 of the 7,196 study subjects (34.1%) had previously received an AR diagnosis; 875 (48.6%) were cases and 1,578 (29.2%) were controls (P

Original languageEnglish
Pages (from-to)1744-1749
Number of pages6
JournalLaryngoscope
Volume124
Issue number8
DOIs
Publication statusPublished - 2014

Keywords

  • Allergic rhinitis
  • nasopharyngeal carcinoma

ASJC Scopus subject areas

  • Otorhinolaryngology

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