多巴胺DRD2基因多型性與手指輕敲測驗的相關性研究

Translated title of the contribution: Associated study between Dopamine DRD2 gene polymorphism and finger tapping test

侯文萱, 陳泰瑞

Research output: Contribution to journalArticle

Abstract

Neurotransmitter dopamine has relation with neuro-psychiatric disease, it also has effect on motor function for healthy individuals and also determines the outcome of rehabilitation for neuro-psychiatric disease patients. Finger Tapping Test (FTT), a neuro-psychological test, is thought to be associated with dopamine. Therefore, the goal of this study is to investigate the association relationship between dopamine genes polymorphism (DRD2 TaqI) and FTT. Method: We recruit healthy Han Chinese, age between 20 and 60 years old, having no neuro-psychiatric illness and family history for dopamine genes polymorphism (DRD2 TaqI) and FTT assessment. Result: Total 106 cases were enrolled in the study. Analysis the relationship between FTT and DRD2 gene polymorphism showed that A1/A2 genotype has higher score of finger tapping test than A1/A1 or A2/A2 genotype (p=0.031). Conclusion: Our results show that there is significant relationship between FTT and DRD2 gene polymorphism.
Translated title of the contributionAssociated study between Dopamine DRD2 gene polymorphism and finger tapping test
Original languageTraditional Chinese
Pages (from-to)245-250
Number of pages6
Journal台灣復健醫學雜誌
Volume37
Issue number4
DOIs
Publication statusPublished - Dec 2009

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