多巴胺DRD2基因多型性與手指輕敲測驗的相關性研究

Translated title of the contribution: Associated study between Dopamine DRD2 gene polymorphism and finger tapping test

侯文萱, 陳泰瑞

Research output: Contribution to journalArticle

Abstract

Neurotransmitter dopamine has relation with neuro-psychiatric disease, it also has effect on motor function for healthy individuals and also determines the outcome of rehabilitation for neuro-psychiatric disease patients. Finger Tapping Test (FTT), a neuro-psychological test, is thought to be associated with dopamine. Therefore, the goal of this study is to investigate the association relationship between dopamine genes polymorphism (DRD2 TaqI) and FTT. Method: We recruit healthy Han Chinese, age between 20 and 60 years old, having no neuro-psychiatric illness and family history for dopamine genes polymorphism (DRD2 TaqI) and FTT assessment. Result: Total 106 cases were enrolled in the study. Analysis the relationship between FTT and DRD2 gene polymorphism showed that A1/A2 genotype has higher score of finger tapping test than A1/A1 or A2/A2 genotype (p=0.031). Conclusion: Our results show that there is significant relationship between FTT and DRD2 gene polymorphism.
Original languageTraditional Chinese
Pages (from-to)245-250
Number of pages6
Journal台灣復健醫學雜誌
Volume37
Issue number4
DOIs
Publication statusPublished - Dec 2009

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