Areca nut may kill cells in a different way

Mei Huei Lin, Shyun Yeu Liu, Young Chau Liu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Areca nut (AN, Areca catechu L.) is a popular but carcinogenic chewing material used by approximately 200-600 million people worldwide. In the past few decades, AN has been discovered to possess genotoxic, cytostatic, and cytotoxic effects on cells. Some ingredients of AN, such as AN extract (ANE), arecoline, hydroxychavicol, and oligomeric procyanidins were demonstrated to stimulate apoptotic and/or growth arresting phenotypes in treated cells. However, our recent studies showed that ANE predominantly induces the autophagic responses, albeit the simultaneous initiation of apoptotic pathway. This finding may renew the knowledge about the cytotoxic effects of AN on oral cells in physiological conditions.

Original languageEnglish
Title of host publicationNuts: Properties, Consumption and Nutrition
PublisherNova Science Publishers Inc
Pages167-172
Number of pages6
ISBN (Print)9781617619786
Publication statusPublished - 2011

Fingerprint

Areca
Nuts
cytotoxicity
arecoline
Areca catechu
Arecoline
Proanthocyanidins
procyanidins
Mastication
extracts
Cytostatic Agents
cells
mastication
mouth
ingredients
Phenotype
phenotype
Growth
betel nut

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Lin, M. H., Liu, S. Y., & Liu, Y. C. (2011). Areca nut may kill cells in a different way. In Nuts: Properties, Consumption and Nutrition (pp. 167-172). Nova Science Publishers Inc.

Areca nut may kill cells in a different way. / Lin, Mei Huei; Liu, Shyun Yeu; Liu, Young Chau.

Nuts: Properties, Consumption and Nutrition. Nova Science Publishers Inc, 2011. p. 167-172.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lin, MH, Liu, SY & Liu, YC 2011, Areca nut may kill cells in a different way. in Nuts: Properties, Consumption and Nutrition. Nova Science Publishers Inc, pp. 167-172.
Lin MH, Liu SY, Liu YC. Areca nut may kill cells in a different way. In Nuts: Properties, Consumption and Nutrition. Nova Science Publishers Inc. 2011. p. 167-172
Lin, Mei Huei ; Liu, Shyun Yeu ; Liu, Young Chau. / Areca nut may kill cells in a different way. Nuts: Properties, Consumption and Nutrition. Nova Science Publishers Inc, 2011. pp. 167-172
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