Apical segmental dysfunction in hypertrophic cardiomyopathy: Progression into end-stage heart failure with sudden cardiac death

Yu Lin Ko, Jiunn Lee Lin, Meng Iiuan Lei, Jin Jer Chen, Shi Sheng Tsou, Peiliang Kuan, Wen Pin Lien

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5 Citations (Scopus)


Apical segmental dysfunction is an unusual finding in hypertrophic cardiomyopathy (HCM). It is characterized by a poor clinical course and a high incidence of malignant ventricular tachyarrhythmias. Long-term prognosis of patients with HCM and apical segmental dysfunction is still unclear. We report 2 cases of apical segmental dysfunction in HCM in whom progressive apical dilatation and congestive heart failure developed. Both patients died suddenly, and intractable ventricular tachyarrhythmias were documented in 1 case during resuscitation. This report provides further evidence that apical segmental dysfunction might predict a subgroup of patients with HCM who are likely to develop end-stage heart failure and are at high risk of sudden cardiac death.

Original languageEnglish
Pages (from-to)436-440
Number of pages5
JournalCardiology (Switzerland)
Issue number5
Publication statusPublished - Jan 1 1995
Externally publishedYes



  • Apical segmental dysfunction
  • Endstage heart failure
  • Hypertrophic cardiomyopathy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

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