Antioxidant iridoid glucosides from Wendlandia formosana

B. Lakshmana Raju; Shwu Jiuan Lin; Wen C. Hou; Zhi Yang Lai; Pan Chun Liu; Feng-Lin Hsu

doi:10.1080/14786410310001622013

Antioxidant iridoid glucosides from Wendlandia formosana

B. Lakshmana Raju, Shwu Jiuan Lin, Wen C. Hou, Zhi Yang Lai, Pan Chun Liu, Feng-Lin Hsu

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Two new iridoid glucosides of 10-O-caffeoyl scandoside methyl ester (3), and 6-methoxy scandoside methyl ester (4) besides the known compounds of scandoside methyl ester (1), methyl deacetyl asperulosidate (2), 10-O-caffeoyl daphylloside (5), phytol (6), and ursolic acid (7) were isolated from the leaves of Wendlandia formosana. Structure elucidation of the new iridoid glucosides was based on interpretation of high-resolution 1D and 2D NMR spectral data and chemical conversions. Antioxidant activity of Compounds (1-5) against diphenylpicrylhydrazyl (DPPH) and hydroxyl radical, and peroxynitrite was reported.

Original language	English
Pages (from-to)	357-364
Number of pages	8
Journal	Natural Product Research
Volume	18
Issue number	4
DOIs	https://doi.org/10.1080/14786410310001622013
Publication status	Published - Aug 2004

Keywords

Antioxidant activity
Iridoid glucosides
Rubiaceae
Scavenging activity
Wendlandia formosana

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Plant Science
Organic Chemistry

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10.1080/14786410310001622013

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title = "Antioxidant iridoid glucosides from Wendlandia formosana",

abstract = "Two new iridoid glucosides of 10-O-caffeoyl scandoside methyl ester (3), and 6-methoxy scandoside methyl ester (4) besides the known compounds of scandoside methyl ester (1), methyl deacetyl asperulosidate (2), 10-O-caffeoyl daphylloside (5), phytol (6), and ursolic acid (7) were isolated from the leaves of Wendlandia formosana. Structure elucidation of the new iridoid glucosides was based on interpretation of high-resolution 1D and 2D NMR spectral data and chemical conversions. Antioxidant activity of Compounds (1-5) against diphenylpicrylhydrazyl (DPPH) and hydroxyl radical, and peroxynitrite was reported.",

keywords = "Antioxidant activity, Iridoid glucosides, Rubiaceae, Scavenging activity, Wendlandia formosana",

author = "Raju, {B. Lakshmana} and Lin, {Shwu Jiuan} and Hou, {Wen C.} and Lai, {Zhi Yang} and Liu, {Pan Chun} and Feng-Lin Hsu",

note = "Funding Information: This work was supported by a grant from the National Science Council of the Republic of China (NSC 89-2323-B-038-001). We thank Ms. Shwu-Hui Wang, Center for Instrumentation, Taipei Medical University, for recording the NMR data and Ms. Shu-Yun Sun (Taipei Regional Analytical Instrumentation Center, NSC) for measurement of the low-and high-resolution FABMS.",

year = "2004",

month = aug,

doi = "10.1080/14786410310001622013",

language = "English",

volume = "18",

pages = "357--364",

journal = "Natural Product Research",

issn = "1478-6419",

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T1 - Antioxidant iridoid glucosides from Wendlandia formosana

AU - Raju, B. Lakshmana

AU - Lin, Shwu Jiuan

AU - Hou, Wen C.

AU - Lai, Zhi Yang

AU - Liu, Pan Chun

AU - Hsu, Feng-Lin

N1 - Funding Information: This work was supported by a grant from the National Science Council of the Republic of China (NSC 89-2323-B-038-001). We thank Ms. Shwu-Hui Wang, Center for Instrumentation, Taipei Medical University, for recording the NMR data and Ms. Shu-Yun Sun (Taipei Regional Analytical Instrumentation Center, NSC) for measurement of the low-and high-resolution FABMS.

PY - 2004/8

Y1 - 2004/8

N2 - Two new iridoid glucosides of 10-O-caffeoyl scandoside methyl ester (3), and 6-methoxy scandoside methyl ester (4) besides the known compounds of scandoside methyl ester (1), methyl deacetyl asperulosidate (2), 10-O-caffeoyl daphylloside (5), phytol (6), and ursolic acid (7) were isolated from the leaves of Wendlandia formosana. Structure elucidation of the new iridoid glucosides was based on interpretation of high-resolution 1D and 2D NMR spectral data and chemical conversions. Antioxidant activity of Compounds (1-5) against diphenylpicrylhydrazyl (DPPH) and hydroxyl radical, and peroxynitrite was reported.

AB - Two new iridoid glucosides of 10-O-caffeoyl scandoside methyl ester (3), and 6-methoxy scandoside methyl ester (4) besides the known compounds of scandoside methyl ester (1), methyl deacetyl asperulosidate (2), 10-O-caffeoyl daphylloside (5), phytol (6), and ursolic acid (7) were isolated from the leaves of Wendlandia formosana. Structure elucidation of the new iridoid glucosides was based on interpretation of high-resolution 1D and 2D NMR spectral data and chemical conversions. Antioxidant activity of Compounds (1-5) against diphenylpicrylhydrazyl (DPPH) and hydroxyl radical, and peroxynitrite was reported.

KW - Antioxidant activity

KW - Iridoid glucosides

KW - Rubiaceae

KW - Scavenging activity

KW - Wendlandia formosana

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Antioxidant iridoid glucosides from Wendlandia formosana

Abstract

Keywords

ASJC Scopus subject areas

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