Antioxidant effects of Chinese traditional medicine: Focus on Trilinolein isolated from the Chinese herb sanchi (Panax pseudoginseng)

P. Chan, B. Tomlinson

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

It is thought that oxygen-derived free radicals (OFR) cause lipid peroxidation, which contributes to the process of atherosclerosis, and they are also involved in the myocardial damage seen with ischemia and reperfusion. Antioxidants could potentially ameliorate such harmful effects. Many natural plant products have been shown to have antioxidant effects. Trilinolein, a triacylglycerol purified from Panax pseudoginseng, which is commonly used in Chinese traditional medicine, has been found to have pharmacological effects, including antioxidant activity that may explain the benefits in treating circulatory disorders perceived from the use of the herb over the centuries. (C) 2000 the American College of Clinical Pharmacology.

Original languageEnglish
Pages (from-to)457-461
Number of pages5
JournalJournal of Clinical Pharmacology
Volume40
Issue number5
Publication statusPublished - 2000

Fingerprint

Panax
Chinese Traditional Medicine
Antioxidants
Lipid Peroxidation
Reperfusion
Free Radicals
Atherosclerosis
Triglycerides
Ischemia
Pharmacology
Oxygen
trilinolein

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

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AB - It is thought that oxygen-derived free radicals (OFR) cause lipid peroxidation, which contributes to the process of atherosclerosis, and they are also involved in the myocardial damage seen with ischemia and reperfusion. Antioxidants could potentially ameliorate such harmful effects. Many natural plant products have been shown to have antioxidant effects. Trilinolein, a triacylglycerol purified from Panax pseudoginseng, which is commonly used in Chinese traditional medicine, has been found to have pharmacological effects, including antioxidant activity that may explain the benefits in treating circulatory disorders perceived from the use of the herb over the centuries. (C) 2000 the American College of Clinical Pharmacology.

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